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[关于使用基于淀粉的血浆扩容剂治疗马休克的初步经验]

[Preliminary experiences with the treatment of shock in horses with a plasma expander from a starch base].

作者信息

Hermann M, Bretscher R, Thiébaud G, Meister D

机构信息

Veterinär-Medizinische Klinik, Universität Zürich.

出版信息

Schweiz Arch Tierheilkd. 1990;132(1):5-12.

PMID:2305232
Abstract

HAES Steril 10% is a colloidal plasma expander rarely used in veterinary medicine. In this study HAES was used in clinical cases for the treatment of shock and in a comparative hypervolemic hemodilution study (HAES versus lactated Ringer's solution) using two experimental horses. Injection of a HAES volume equivalent to 10% of estimated blood volume resulted in a highly significant drop in PCV and in a significant drop in total protein concentration. Half live of HAES was approximately two hours. No incompatibility reactions were observed. In man HAES improves microcirculation. Studies in progress may confirm a similar effect in the equine.

摘要

贺斯 Steril 10%是一种在兽医学中很少使用的胶体血浆扩容剂。在本研究中,贺斯被用于临床病例中的休克治疗,并在一项使用两匹实验马的比较性高血容量血液稀释研究(贺斯与乳酸林格氏液对比)中使用。注射相当于估计血容量10%的贺斯体积会导致红细胞压积显著下降和总蛋白浓度显著下降。贺斯的半衰期约为两小时。未观察到不相容反应。在人类中,贺斯可改善微循环。正在进行的研究可能会证实其在马身上有类似效果。

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