Department of Gynecology and Obstetrics, St. Elisabeth Krankenhaus-Hohenlind, Werthmannstr. 1, 50935 Cologne, Germany.
Arch Gynecol Obstet. 2013 Mar;287(3):455-62. doi: 10.1007/s00404-012-2559-0. Epub 2012 Oct 9.
The objective of this research was to identify the rate of unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH) and describe the therapy regime.
The research is based on a retrospective chart analysis of patients undergoing a simple hysterectomy in the gynecological endoscopy department of a general hospital in Germany.
2,577 simple hysterectomies conducted between March 2005 and March 2010 were sub-classified in different types of hysterectomies (vaginal-, abdominal-, total-, abdominal supracervical hysterectomy, LAVH, and LASH). This study focuses on the LASH sub-group of 1,584 patients and does not make any comparisons to other operative approaches. Out of the 1,584 patients, 87.8 % (n = 1,391) received preoperative screening to exclude dysplasia or malignancy based on the policy of the German Association for gynecology and obstetrics (DGGG). The screening includes cytology (Pap-smear) and preoperative ultrasound of the uterus or dilatation and curettage (d&c). Unexpected malignancies were found in 0.25 % (n = 4) of the patients pre-screened according to DGGG protocol. Out of the four malign patients, two had endometrial cancer. Two patients had leiomyosarcoma.
The study shows that there is a small probability of unexpected malignancies even in correctly pre-screened patients for LASH procedures. Yet in the short-term (28-52 months), malign patients remain recurrence free after treatment. LASH is therefore a good procedure for assumed benign disease.
本研究旨在确定腹腔镜辅助经宫颈子宫切除术(LASH)后意外恶性肿瘤的发生率,并描述治疗方案。
本研究基于德国一家综合医院妇科内镜科行单纯子宫切除术患者的回顾性图表分析。
2005 年 3 月至 2010 年 3 月期间共进行了 2577 例单纯子宫切除术,分为不同类型的子宫切除术(阴道、腹部、全子宫、腹部经宫颈子宫切除术、LAVH 和 LASH)。本研究重点关注 LASH 亚组的 1584 例患者,且不与其他手术方法进行任何比较。在 1584 例患者中,87.8%(n=1391)根据德国妇科和产科协会(DGGG)的政策进行了术前筛查,以排除发育不良或恶性肿瘤。筛查包括细胞学(巴氏涂片)和子宫术前超声或扩张和刮宫术(d&c)。根据 DGGG 方案进行预筛查的患者中,有 0.25%(n=4)发现意外恶性肿瘤。在这 4 例恶性肿瘤患者中,2 例为子宫内膜癌,2 例为平滑肌肉瘤。
该研究表明,即使对 LASH 手术进行了正确的预筛查,仍有发生意外恶性肿瘤的小概率。然而,在短期(28-52 个月)内,恶性肿瘤患者在治疗后仍无复发。因此,LASH 是一种治疗良性疾病的良好方法。