Davis S, Andrews J, Lichtenstein M, Kaye A, Tress B, Rossiter S, Salehi N, Binns D
University Department of Medicine, Royal Melbourne Hospital, Australia.
Stroke. 1990 Feb;21(2):252-9. doi: 10.1161/01.str.21.2.252.
We used single-photon emission computed tomography with technetium-99m hexamethylpropylene amine oxime in 18 studies on 13 patients with subarachnoid hemorrhage to determine whether any changes in cerebral blood flow could be correlated with clinical or computed tomographic evidence of delayed ischemia. Among the seven patients without focal neurologic deficits, regional cerebral hypoperfusion was demonstrated in only one who died. Among the 10 patients with aneurysmal subarachnoid hemorrhage, one died before surgery, and six developed postoperative delayed ischemic deficits, of whom two died. Among the patients with angiographically documented aneurysms, regional hypoperfusion correlated with the presence and severity of delayed neurologic deficits, whereas correlative computed tomographic scans showed either early infarction or no relevant abnormality. This technique facilitates early diagnosis of cerebral tissue hypoperfusion due to vasospasm after subarachnoid hemorrhage.
我们对13例蛛网膜下腔出血患者进行了18项研究，使用锝-99m六甲基丙烯胺肟单光子发射计算机断层扫描，以确定脑血流量的任何变化是否与临床或计算机断层扫描显示的迟发性缺血证据相关。在7例无局灶性神经功能缺损的患者中，仅1例死亡患者出现了局部脑灌注不足。在10例动脉瘤性蛛网膜下腔出血患者中，1例在手术前死亡，6例出现术后迟发性缺血性缺损，其中2例死亡。在血管造影证实有动脉瘤的患者中，局部灌注不足与迟发性神经功能缺损的存在和严重程度相关，而相关的计算机断层扫描显示早期梗死或无相关异常。这项技术有助于早期诊断蛛网膜下腔出血后因血管痉挛导致的脑组织灌注不足。
