Mayer Erik K, Undre Shabnam, Cohen Daniel C, Walker Marjorie M, Vale Justin A, Patel Anup
Department of Urology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, Praed Street, London W2 1NY, UK.
Case Rep Oncol Med. 2012;2012:480826. doi: 10.1155/2012/480826. Epub 2012 Sep 29.
Bladder lymphomas are rarely primary tumours and more commonly associated with systemic lymphoma, either as nonlocalised bladder lymphoma or as secondary bladder lymphoma. Primary bladder lymphomas (PBL) tend to be low-grade mucosa-associated lymphoid tissue (MALT) type, contrasting with diffuse large cell or follicular centre cell types more commonly seen in secondary bladder lymphoma. Bladder involvement by systemic lymphoma infers poor prognosis and patients often have no localising symptoms (typically a postmortem diagnosis). Other treatments are preferred over surgery for all bladder lymphomas, except where diagnosis is uncertain or for relief of irritative bladder symptoms. We describe a unique case of systemic high-grade B-cell lymphoma with simultaneous cutaneous renal and bladder lesions at presentation.
膀胱淋巴瘤很少是原发性肿瘤，更常见的是与全身性淋巴瘤相关，表现为非局限性膀胱淋巴瘤或继发性膀胱淋巴瘤。原发性膀胱淋巴瘤（PBL）往往是低级别黏膜相关淋巴组织（MALT）型，这与继发性膀胱淋巴瘤中更常见的弥漫性大细胞或滤泡中心细胞类型形成对比。全身性淋巴瘤累及膀胱提示预后不良，患者通常没有定位症状（通常是尸检诊断）。除诊断不确定或为缓解膀胱刺激症状外，对于所有膀胱淋巴瘤，其他治疗方法优于手术。我们描述了一例独特的全身性高级别B细胞淋巴瘤病例，该病例在就诊时同时出现皮肤、肾脏和膀胱病变。
