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吸入氟替卡松致一名患有囊性纤维化和晚期肝病的青少年肾上腺危象:病例报告

Adrenal crisis caused by inhaled fluticasone in an adolescent with cystic fibrosis and advanced hepatopathy: a case report.

作者信息

Denne C, Vogl-Voswinckel A E, Gruebl A, Burdach S

机构信息

Department of Pediatrics, Kinderklinik München Schwabing, Klinikum Schwabing StKM GmbH and Klinikum Rechts der Isar (AöR) of the Technical University (TU) München, 80804 Munich, Germany.

出版信息

Case Rep Pulmonol. 2012;2012:913574. doi: 10.1155/2012/913574. Epub 2012 Sep 29.

Abstract

Inhaled corticosteroids are widely accepted in the treatment of cystic fibrosis. Long-term use may cause systemic complications, especially high-dose fluticasone. We report about a young man who presented with encephalopathy after excessive physical activity caused by secondary adrenal insufficiency. He recovered quickly after systemic corticosteroid replacement therapy. This problem is considered to be underdiagnosed in clinical practice.

摘要

吸入性糖皮质激素在囊性纤维化的治疗中被广泛接受。长期使用可能会引起全身并发症,尤其是高剂量氟替卡松。我们报告了一名年轻男性,他因继发性肾上腺功能不全导致过度体力活动后出现脑病。在接受全身性糖皮质激素替代治疗后,他很快康复。这个问题在临床实践中被认为诊断不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47c0/3465889/af0279a1ae3d/CRIM.PULMONOLOGY2012-913574.001.jpg

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