Korman S H
Department of Pediatrics, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.
Am J Clin Nutr. 1990 Feb;51(2):139-41. doi: 10.1093/ajcn/51.2.139.
Persistent pica may be either a cause or a result of iron deficiency. Three children are described with long-standing pica and iron-deficiency anemia and in whom total villous atrophy consistent with celiac disease was found on jejunal biopsy. Additional findings included short stature, delayed bone age, and impaired xylose absorption. A dramatic growth spurt and complete resolution of pica were observed after a gluten-free diet. In these cases pica evidently resulted from iron deficiency secondary to malabsorption. Underlying celiac disease should be considered in children with persistent pica and growth failure even if gastrointestinal disturbances are minimal.
持续性异食癖可能是缺铁的原因或结果。本文描述了三名患有长期异食癖和缺铁性贫血的儿童，他们的空肠活检发现有与乳糜泻相符的全绒毛萎缩。其他发现包括身材矮小、骨龄延迟和木糖吸收受损。采用无麸质饮食后，观察到患儿出现显著的生长突增且异食癖完全消失。在这些病例中，异食癖显然是由吸收不良继发的缺铁所致。即使胃肠道紊乱症状轻微，对于患有持续性异食癖和生长发育迟缓的儿童，也应考虑潜在的乳糜泻。
