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[颈内动脉病理性扭曲的外科治疗]

[Surgical treatment of pathological kinking of the internal carotid artery].

作者信息

Dadashov S A, Lavrent'ev A V, Frolov K B, Vinogradov O A, Dziundzia A N, Ul'ianov N D

出版信息

Angiol Sosud Khir. 2012;18(3):116-21.

Abstract

The study was aimed at improving surgical policy in management of patients presenting with pathological tortuosity of the internal carotid artery. The study comprised a total of 105 patients with pathological kinking of the internal carotid artery undergoing a total of 117 reconstructive operations. In order to determine the indications for the operation the patients were subjected to triplex scanning, transcranial Dopplerography and monitoring of blood flow in the median cerebral artery, contrast-enhanced computed tomography or magnetic resonance tomography. Depending upon the degree of intimal proliferation in the area of the maximal bend («septal tortuosity»), the patients were divided into two groups: group I - pathological kinking of the internal carotid artery without intimal proliferation - 75 patients, Group II - pathological kinking with intimal proliferation - 30 patients. The indications for the operation were determined depending upon the degree of cerebrovascular insufficiency, haemodynamical significance of pathological tortuosity, the presence of intimal proliferation in the zone of the maximal bend - «septal tortuosity». An operation of choice for Group I patients was resection of the internal carotid artery with redressation and reimplantation into the own bed, and all Group II patients underwent resection of the area of kinking of the internal carotid artery with an end-to-end anastomosis in order to remove the septal portion. Immediately after the operation 85% of patients were found to have their cardiovascular insufficiency symptoms relieved and all patients showed improved haemodynamic parameters (p<0.01). Neither postoperative strokes nor lethal outcomes were registered.

摘要

该研究旨在改进对患有颈内动脉病理性迂曲患者的手术策略。该研究共纳入了105例患有颈内动脉病理性扭结的患者,共进行了117次重建手术。为了确定手术适应症,对患者进行了三联扫描、经颅多普勒检查以及大脑中动脉血流监测、增强计算机断层扫描或磁共振断层扫描。根据最大弯曲区域(“间隔迂曲”)内膜增生的程度,将患者分为两组:第一组——无内膜增生的颈内动脉病理性扭结——75例患者,第二组——有内膜增生的病理性扭结——30例患者。根据脑血管供血不足的程度、病理性迂曲的血流动力学意义、最大弯曲区域(“间隔迂曲”)内膜增生的情况来确定手术适应症。第一组患者的首选手术是切除颈内动脉并矫正后重新植入原位,所有第二组患者均接受颈内动脉扭结区域切除并进行端端吻合,以切除间隔部分。术后立即发现85%的患者心血管供血不足症状得到缓解,所有患者的血流动力学参数均有所改善(p<0.01)。未记录到术后中风或致死情况。

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