Department of Internal Medicine, Mount Sinai School of Medicine, New York, NY, USA.
Cardiol Rev. 2013 May-Jun;21(3):121-6. doi: 10.1097/CRD.0b013e318277c990.
Paradigms are a part of our human nature. In the world of medicine and science, they allow investigators to work within a particular, previously accepted framework that provides certain constraints. This is the crux of Newton's quote, "If I've seen so far it's because I stood upon the shoulders of giants." However, in the same way that it allows us to build, it can constrain our thought processes if we fail to accept new data that are ill suited to an accepted paradigm. The physiological mechanisms to explain the phenomenon of chronic congestive heart failure are similar to other paradigms of science, in that they have undergone several shifts throughout their history, and continue to change with new evidence. Here, we seek to explore how our understanding of congestive heart failure has changed.
范式是我们人类本性的一部分。在医学和科学领域，它们允许研究人员在一个特定的、先前被接受的框架内工作，这个框架提供了一定的限制。这就是牛顿名言的关键所在：“如果说我看得比别人更远些，那是因为我站在巨人的肩膀上。”然而，同样地，它允许我们进行构建，如果我们未能接受不适合已接受范式的新数据，它也会限制我们的思维过程。解释慢性充血性心力衰竭现象的生理机制与科学的其他范式类似，因为它们在历史上经历了几次转变，并随着新证据不断变化。在这里，我们试图探讨我们对充血性心力衰竭的理解是如何改变的。
