偏头痛伴先兆与单侧皮质血管通透性增加相关。
Migraine with aura associated with unilateral cortical increase in vascular permeability.
机构信息
Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Canada.
出版信息
Cephalalgia. 2012 Dec;32(16):1216-9. doi: 10.1177/0333102412462286. Epub 2012 Oct 12.
BACKGROUND
Few studies to date have captured perfusion and vascular permeability changes during a migraineur's aura. This may be important information to the clinician in the context of the differential diagnosis of migraine with aura versus acute stroke.
SUMMARY
We report a case in which magnetic resonance perfusion during a migraine aura showed unilateral hypoperfusion differentially affecting gray and white matter and was associated with a hemispheric increase in permeability.
CONCLUSIONS
Imaging in this case suggests that migraine aura is associated with oligemia below the threshold for infarction. Increased vascular permeability may be a critical mechanism contributing to perfusion changes observed in migraine with aura.
背景
目前为止，很少有研究能够捕捉偏头痛先兆期的灌注和血管通透性变化。对于偏头痛伴先兆与急性卒中超额诊断的临床医生来说，这可能是重要的信息。
摘要
我们报告了一个病例，在偏头痛先兆期进行磁共振灌注时，发现单侧灌注不足，差异影响灰质和白质，并伴有半球通透性增加。
结论
该病例的影像学检查提示偏头痛先兆与低于梗死阈值的低灌注有关。增加的血管通透性可能是导致偏头痛先兆中观察到的灌注变化的关键机制。
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