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髓母细胞瘤的超微结构研究

Ultrastructural study of medullomyoblastoma.

作者信息

Walter G F, Brucher J M

出版信息

Acta Neuropathol. 1979 Dec;48(3):211-4. doi: 10.1007/BF00690521.

DOI:10.1007/BF00690521
PMID:230690
Abstract

A case of cerebellar medullomyoblastoma in a young boy was investigated by electron microscopy. The neuroectodermal component shows the characteristics of a desmoplastic medulloblastoma. The mesodermal component consists of more or less differentiated cross-striated muscle cells. Undifferentiated muscle cells are very similar to proliferated endothelial cells of blood vessels within the muscular component, so that an origin of this component from pluripotential endothelial cells of the vessel wall is suggested. This tumor is considered a malignant teratoid because of the derivation from two blastodermic layers and because of the midline localization in children suggesting a malformative origin.

摘要

一名小男孩的小脑髓母细胞瘤病例通过电子显微镜进行了研究。神经外胚层成分显示出促纤维增生性髓母细胞瘤的特征。中胚层成分由或多或少分化的横纹肌细胞组成。未分化的肌细胞与肌肉成分内血管增生的内皮细胞非常相似,因此提示该成分起源于血管壁的多能内皮细胞。由于该肿瘤起源于两个胚层且在儿童中位于中线提示有畸形起源,所以被认为是恶性畸胎瘤。

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1
Ultrastructural study of medullomyoblastoma.髓母细胞瘤的超微结构研究
Acta Neuropathol. 1979 Dec;48(3):211-4. doi: 10.1007/BF00690521.
2
[Ultrastructural study of a medullomyoblastoma (author's transl)].[髓母细胞瘤的超微结构研究(作者译)]
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The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors.小脑髓母细胞瘤及其与原始神经外胚层肿瘤的关系。
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引用本文的文献

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Asian J Neurosurg. 2016 Jul-Sep;11(3):315-6. doi: 10.4103/1793-5482.144167.
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Medulloblastoma with myogenic differentiation: long-term survival in a patient treated with aggressive combination therapy and autologous stem cell transplantation.具有成肌分化的髓母细胞瘤:接受强化联合治疗和自体干细胞移植治疗的患者的长期生存。
J Neurooncol. 2011 Dec;105(3):659-62. doi: 10.1007/s11060-011-0626-1. Epub 2011 Jun 19.
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Ultrastructural aspects of myogenesis found in neoplasms.

本文引用的文献

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Cystic teratomas and teratoid tumors of the central nervous system in infancy and childhood.婴幼儿及儿童期中枢神经系统的囊性畸胎瘤和类畸胎瘤
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肿瘤中发现的肌发生的超微结构特征。
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Cancer. 1970 Jun;25(6):1279-85. doi: 10.1002/1097-0142(197006)25:6<1279::aid-cncr2820250605>3.0.co;2-p.
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Primary cerebral rhabdomyosarcoma and the problem of medullomyoblastoma.原发性脑横纹肌肉瘤与髓母细胞瘤问题
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[On congenital mixed tumors of the cerebellum].[关于小脑先天性混合瘤]
Dtsch Z Nervenheilkd. 1966 Oct 24;189(4):354-74.
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Fine structure of myomedulloblastoma.肌母髓细胞瘤的精细结构
Acta Neuropathol. 1977 Jan 31;37(1):43-8. doi: 10.1007/BF00684539.
10
Heterotopic striated muscle on the surface of the brain.大脑表面的异位横纹肌。
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