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经直肠前列腺近距离放射治疗中放射性粒子种植导致直肠损伤。

Rectal injury during permanent seed implantation for prostate brachytherapy.

机构信息

Department of Urology, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama 230-8765, Japan.

出版信息

Jpn J Clin Oncol. 2012 Dec;42(12):1207-10. doi: 10.1093/jjco/hys165. Epub 2012 Oct 15.

Abstract

Serious complications have not been previously reported during seed implantation for prostate brachytherapy. We present an unreported case of rectal injury caused by an ultrasound probe. A 67-year-old male presented with a serum prostate-specific antigen level of 5.50 ng/ml, a Gleason score of 7 (3 + 4) and clinical T2a adenocarcinoma of the prostate. A transperineal permanent prostate brachytherapy implantation was performed. The patient subsequently complained of abdominal pain postoperatively. A gastrointestinal perforation was suspected based on an abdominal X-ray obtained on the day after the brachytherapy. Rectal injury was recognized during an exploratory laparotomy, and a primary closure and temporary diversion ileostomy were performed. The healing of the injury was confirmed by colonoscopy and an ileostomy closure was performed 2 months after the temporary diversion. The investigating committee for this accident concluded that the ultrasound probe had perforated the rectum. This is the first case of a rectal injury during seed implantation for prostate brachytherapy.

摘要

先前未曾报道过前列腺近距离放射治疗中种子植入时出现严重并发症。我们报告一例由超声探头引起的直肠损伤的罕见病例。一名 67 岁男性,血清前列腺特异性抗原水平为 5.50ng/ml,Gleason 评分为 7(3+4),临床 T2a 前列腺腺癌。行经会阴永久性前列腺近距离放射治疗植入术。患者术后出现腹痛。根据植入术后次日的腹部 X 线片怀疑出现胃肠道穿孔。剖腹探查时发现直肠损伤,并进行了一期缝合和暂时性回肠造口术。2 个月后行临时回肠造口关闭时,通过结肠镜检查确认了损伤的愈合。该事故调查委员会得出结论,超声探头刺穿了直肠。这是首例前列腺近距离放射治疗中种子植入时发生直肠损伤的病例。

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