Ryder T A, Mobberley M A, Hughes L, Hendry W F
Electron Microscopy Unit, Queen Charlotte's and Chelsea Hospital, London, United Kingdom.
Fertil Steril. 1990 Mar;53(3):556-60. doi: 10.1016/s0015-0282(16)53357-3.
The sperm tails of 400 patients having absent or impaired sperm motility were examined by electron microscopy. A wide variety of fine-structural defects were observed although all of the patients fell into clearly defined groups. Total or partial dynein arm deficiency was observed in 12 patients (3%). Ninety-one patients (23%) had sperm with a spectrum of fine-structural defects, whereas 90 patients (23%) were necrospermic. Subjects with low motility, but with at least a few tails of normal structure, had a 5% pregnancy rate, whereas those patients with similar overall motility, but in whom no normal sperm were seen, produced no pregnancies. The results confirm the importance of making an electron microscopical examination of the sperm of patients with asthenozoospermia.
对400例精子活力缺失或受损患者的精子尾部进行了电子显微镜检查。尽管所有患者都可明确分组，但观察到了各种各样的细微结构缺陷。12例患者（3%）出现了完全或部分动力蛋白臂缺失。91例患者（23%）的精子存在一系列细微结构缺陷，而90例患者（23%）为死精症。精子活力低但至少有一些结构正常的尾部的患者，其妊娠率为5%，而那些总体活力相似但未见正常精子的患者则未产生妊娠。结果证实了对弱精子症患者的精子进行电子显微镜检查的重要性。
