Stockard J E, Curran J S
University of South Florida College of Medicine, Department of Pediatrics, Tampa.
Ear Hear. 1990 Feb;11(1):21-8. doi: 10.1097/00003446-199002000-00006.
Auditory brain stem responses (ABRs) of 33 high risk, full term or near term newborns with transient elevation of ABR threshold (transient group) were compared with those of normal infants (normal group) and high-risk infants with known conductive (conductive group) and known sensorineural hearing loss (sensorineural group). ABRs of infants in the transient group initially were not significantly different from those of the conductive group in terms of wave I latency, wave V latency, and the slope of the latency-intensity (L-l) function of wave V. In infants with transient unilateral threshold elevation, significantly shorter interpeak latencies were recorded in the affected ear than in the ear that passed. This finding has been previously described in infants with conductive disorders. On follow-up, ABRs in the transient group closely resembled those of the normal group with respect to the same measures. Otologic histories in the transient group were unremarkable in the majority of cases. Increased slope of the L-l function in infants with confirmed conductive disorders was an unexpected finding. Previous studies of patients with conductive loss had not revealed a significant deviation from normal for this measure. An age interaction for the effect might explain the discrepancy between this and previous studies.
对33名具有听觉脑干反应（ABR）阈值短暂升高的高危足月或近足月新生儿（短暂组）的听觉脑干反应，与正常婴儿（正常组）、已知传导性听力损失的高危婴儿（传导组）和已知感音神经性听力损失的高危婴儿（感音神经性组）的听觉脑干反应进行了比较。短暂组婴儿的ABR在波I潜伏期、波V潜伏期以及波V的潜伏期-强度（L-I）函数斜率方面，最初与传导组婴儿的ABR并无显著差异。在短暂单侧阈值升高的婴儿中，患侧记录到的峰间潜伏期明显短于通过检测的耳朵。这一发现先前在患有传导性疾病的婴儿中已有描述。随访时，短暂组婴儿的ABR在相同测量指标方面与正常组非常相似。在大多数情况下，短暂组的耳科病史并无异常。确诊为传导性疾病的婴儿中L-I函数斜率增加是一个意外发现。先前对传导性听力损失患者的研究并未显示该测量指标与正常情况有显著偏差。年龄交互作用可能解释了本研究与先前研究之间的差异。
