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对一些埃及海藻的植物化学和生物学研究。

Phytochemical and biological studies on some Egyptian seaweeds.

作者信息

Elsayed Khaled N M, Radwan Mohamed M, Hassan Sherif H M, Abdelhameed Mohamed S, Ibraheem Ibraheem B, Ross Samir A

机构信息

Department of Botany, Faculty of Science, Beni-Suef University, Egypt.

出版信息

Nat Prod Commun. 2012 Sep;7(9):1209-10.

Abstract

Extracts of four species of seaweeds, Ulva lactuca L. (green), Liagora farinosa Lamouroux (red), Padina pavonia L. and Turbinaria ornata Turn (brown), were screened for their antimicrobial, and antimalarial activities, and binding affinity for human opioid receptors. Phytochemical analysis led to the isolation and identification of 10 constituents: fucosterol, stearic acid, palmitic acid, palmitoleic acid, oleic acid, myristic acid, p-hydroxybenzoic acid, beta-sitosterol, glycerol-1-olyl-3-palmotyl-2-galactoside, and glycerol-1,3-diolyl, The last two compounds displayed strong binding affinity to delta opioid receptors.

摘要

对四种海藻提取物进行了筛选,包括石莼(绿色)、粉质软骨藻(红色)、团扇藻和刺松藻(棕色),检测其抗菌、抗疟活性以及与人阿片受体的结合亲和力。植物化学分析导致分离并鉴定出10种成分:岩藻甾醇、硬脂酸、棕榈酸、棕榈油酸、油酸、肉豆蔻酸、对羟基苯甲酸、β-谷甾醇、甘油-1-油基-3-棕榈酰-2-半乳糖苷和甘油-1,3-二油基。最后两种化合物对δ阿片受体表现出强烈的结合亲和力。

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