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基于医院的人芽囊原虫感染的流行病学和临床数据研究。

A hospital-based study of epidemiological and clinical data on Blastocystis hominis infection.

机构信息

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

Foodborne Pathog Dis. 2012 Dec;9(12):1077-82. doi: 10.1089/fpd.2012.1177. Epub 2012 Oct 17.

Abstract

Blastocystis hominis is a foodborne protozoan found in the human feces worldwide. One hundred and ninety-nine individuals with stool samples positive for B. hominis were identified from a pool of 14,325 patient stools collected between 2003 and 2010 from Srinagarind hospital in Thailand. The medical records of patients were reviewed for demographic and clinical data. Of the 85 patients (42.7%) who had B. hominis infection with no co-infections, 42.5% experienced gastrointestinal symptoms. Abdominal pain is the most frequently observed symptom followed by diarrhea. Strongyloides stercolaris and Opisthorchis viverrini were the predominant parasitic co-infections in blastocystosis patients. The infection rates of B. hominis were high during the rainy season. Most B. hominis-infected patients (94%) had underlying diseases; malignancy and chronic diseases were equally top ranked (35.3%) which indicated that B. hominis is an opportunistic protozoan.

摘要

人芽囊原虫是一种食源性原生动物,存在于全球人类粪便中。从 2003 年至 2010 年在泰国诗里叻医院采集的 14325 份患者粪便中,鉴定出 199 名粪便样本中存在人芽囊原虫阳性的个体。对患者的病历进行了人口统计学和临床数据回顾。在 85 名(42.7%)没有合并感染的人芽囊原虫感染者中,42.5%有胃肠道症状。腹痛是最常观察到的症状,其次是腹泻。在芽囊原虫病患者中,最常见的寄生虫合并感染是粪类圆线虫和华支睾吸虫。人芽囊原虫的感染率在雨季较高。大多数(94%)感染人芽囊原虫的患者有基础疾病;恶性肿瘤和慢性病同样排名靠前(35.3%),这表明人芽囊原虫是一种机会性原生动物。

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