Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Stanford University School of Medicine, Palo Alto, CA 94304, USA.
Pediatr Infect Dis J. 2013 Mar;32(3):289-91. doi: 10.1097/INF.0b013e3182784867.
Ethanol lock therapy has been implemented to prevent infections of central venous catheters as well as to treat infections. Fungal catheter-associated blood stream infections are historically more difficult to treat and have required removal of central venous catheters. We report the largest case series to date, successfully treating 5 of 7 fungal catheter-associated blood stream infections with ethanol lock therapy and systemic echinocandin administration.
乙醇封管疗法已被应用于预防和治疗中心静脉导管相关感染。真菌感染所致的导管相关性血流感染历来更难治疗，往往需要拔除中心静脉导管。我们报告了迄今为止最大的病例系列，通过乙醇封管疗法和系统给予棘白菌素成功治疗了 7 例真菌性导管相关性血流感染中的 5 例。
