[短孕期间隔的危险因素及围产期后果：一项回顾性病例对照研究]

[Risk factors and perinatal consequences of short interpregnancy interval: a retrospective case-control study].

作者信息

Vandenbroucke L, Lavoué V, Voltzenlogel M-C, Le Guellec M, Lassel L, Isly H, Poulain P, Morcel K

机构信息

Service d'obstétrique, CHU Anne-de-Bretagne, 16, boulevard de Bulgarie, BP 90347, 35203 Rennes cedex 2, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2013 Apr;42(2):166-73. doi: 10.1016/j.jgyn.2012.09.010. Epub 2012 Oct 15.

DOI:10.1016/j.jgyn.2012.09.010

PMID:23079544

Abstract

OBJECTIVES

To study the maternal risk factors and perinatal complications of a short interpregnancy interval.

PATIENTS AND METHODS

Retrospective case-control study between 2007 and 2009, comparing a group with a short interpregnancy interval (less than 9 months, n=83), and a control group (interval between two pregnancies between 18 and 24 months, n=166).

RESULTS

The main risk factor of short interpregnancy interval is to be unemployed (OR=3.2, P<0.001). There is a significant link between lack of prescription contraceptives in postpartum and a short interval between pregnancies (OR=3.4, P<0.001). We also found a higher rate of anemic women during pregnancy (OR=4.9, P=0.001) and postpartum (OR=2.1, P=0.02) in case of short interpregnancy interval. Short interpregnancy interval increases risk of small for gestational age (OR=2.4, P=0.05) and thermoregulation disorders (OR=3.1, P=0.02).

CONCLUSION

A low socioeconomic level is a risk factor of short interpregnancy interval. Short interpregnancy interval is at risk of maternal iron deficiency and neonatal complications like low birth weight and hypothermia.

摘要

目的

研究妊娠间隔短的孕产妇危险因素及围产期并发症。

患者与方法

2007年至2009年进行回顾性病例对照研究，比较妊娠间隔短（少于9个月，n = 83）的一组与对照组（两次妊娠间隔为18至24个月，n = 166）。

结果

妊娠间隔短的主要危险因素是失业（比值比= 3.2，P <0.001）。产后缺乏处方避孕药与妊娠间隔短之间存在显著关联（比值比= 3.4，P <0.001）。我们还发现，妊娠间隔短的情况下，孕期（比值比= 4.9，P = 0.001）和产后（比值比= 2.1，P = 0.02）贫血女性的比例更高。妊娠间隔短会增加小于胎龄儿的风险（比值比= 2.4，P = 0.05）和体温调节障碍的风险（比值比= 3.1，P = 0.02）。