Vandenbroucke L, Lavoué V, Voltzenlogel M-C, Le Guellec M, Lassel L, Isly H, Poulain P, Morcel K
Service d'obstétrique, CHU Anne-de-Bretagne, 16, boulevard de Bulgarie, BP 90347, 35203 Rennes cedex 2, France.
J Gynecol Obstet Biol Reprod (Paris). 2013 Apr;42(2):166-73. doi: 10.1016/j.jgyn.2012.09.010. Epub 2012 Oct 15.
To study the maternal risk factors and perinatal complications of a short interpregnancy interval.
Retrospective case-control study between 2007 and 2009, comparing a group with a short interpregnancy interval (less than 9 months, n=83), and a control group (interval between two pregnancies between 18 and 24 months, n=166).
The main risk factor of short interpregnancy interval is to be unemployed (OR=3.2, P<0.001). There is a significant link between lack of prescription contraceptives in postpartum and a short interval between pregnancies (OR=3.4, P<0.001). We also found a higher rate of anemic women during pregnancy (OR=4.9, P=0.001) and postpartum (OR=2.1, P=0.02) in case of short interpregnancy interval. Short interpregnancy interval increases risk of small for gestational age (OR=2.4, P=0.05) and thermoregulation disorders (OR=3.1, P=0.02).
A low socioeconomic level is a risk factor of short interpregnancy interval. Short interpregnancy interval is at risk of maternal iron deficiency and neonatal complications like low birth weight and hypothermia.
研究妊娠间隔短的孕产妇危险因素及围产期并发症。
2007年至2009年进行回顾性病例对照研究，比较妊娠间隔短（少于9个月，n = 83）的一组与对照组（两次妊娠间隔为18至24个月，n = 166）。
妊娠间隔短的主要危险因素是失业（比值比= 3.2，P <0.001）。产后缺乏处方避孕药与妊娠间隔短之间存在显著关联（比值比= 3.4，P <0.001）。我们还发现，妊娠间隔短的情况下，孕期（比值比= 4.9，P = 0.001）和产后（比值比= 2.1，P = 0.02）贫血女性的比例更高。妊娠间隔短会增加小于胎龄儿的风险（比值比= 2.4，P = 0.05）和体温调节障碍的风险（比值比= 3.1，P = 0.02）。
社会经济水平低是妊娠间隔短的一个危险因素。妊娠间隔短存在孕产妇缺铁以及新生儿出现低出生体重和体温过低等并发症的风险。
