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重复头颅计算机断层扫描在初始头颅CT阳性的轻度创伤性脑损伤患者管理中的作用

The role of repeat head computed tomography in the management of mild traumatic brain injury patients with a positive initial head CT.

作者信息

Sharifuddin Ashraf, Adnan Johari, Ghani Abdul Rahman, Abdullah Jafri Malin

机构信息

Department of Neurosciences, Hospital Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.

出版信息

Med J Malaysia. 2012 Jun;67(3):305-8.

Abstract

This was a prospective observational study done to evaluate the role of a repeat head CT in patients with mild traumatic brain injury. The aim was to evaluate wether the repeat head CT were useful in providing information that leads to any neurosurgical intervention. 279 adult patients with a mild head injury (GCS 13-15) were enrolled, and these comprised of patients with an initial traumatic intracranial haemorrhage not warranting any surgical intervention. All patients were subjected to a repeat head CT within 48 hours of admission and these showed no change or improvements of the brain lesion in 217 patients (79.2%) and worsening in 62 patients (20.8%). In thirty-one patients, surgical intervention was done following the repeat head CT. All of these patients had a clinical deterioration prior to the repeat head CT. Even if a repeat head CT had not been ordered on these patients, they would have had a repeat head CT due to deteriorating neurological status. When the 62 patients with a worsening repeat head CT were compared with the 217 patients with an improved or unchanged repeat head CT, they were found to have older age, lower GCS on admission, presenting symptoms of headache, higher incidence of multiple traumatic intracranial pathology and lower haemoglobin level on admission. On stepwise multiple logistic regression analysis, three factors were found to independently predict a worse repeat head CT (Table IV). This includes age of 65 years or older, GCS score of less than 15 and multiple traumatic intracranial lesion on initial head CT. As a conclusion, we recommend that, in patients with a MTBI and a normal neurological examination, a repeat cranial CT is not indicated, as it resulted in no change in management or neurosurgical intervention. Close monitoring is warranted in a subset of patients with risk factors for a worsening repeat head CT.

摘要

这是一项前瞻性观察性研究,旨在评估重复头颅CT在轻度创伤性脑损伤患者中的作用。目的是评估重复头颅CT是否有助于提供导致任何神经外科干预的信息。纳入了279例轻度颅脑损伤(格拉斯哥昏迷量表评分13 - 15分)的成年患者,这些患者最初有创伤性颅内出血但无需任何手术干预。所有患者在入院后48小时内接受了重复头颅CT检查,结果显示217例患者(79.2%)脑损伤无变化或有所改善,62例患者(20.8%)病情恶化。31例患者在重复头颅CT检查后接受了手术干预。所有这些患者在重复头颅CT检查前临床症状均有恶化。即使未对这些患者进行重复头颅CT检查,由于神经功能状态恶化,他们也会接受重复头颅CT检查。将62例重复头颅CT检查结果恶化的患者与217例检查结果改善或无变化的患者进行比较,发现前者年龄较大、入院时格拉斯哥昏迷量表评分较低、有头痛症状、多发创伤性颅内病变发生率较高且入院时血红蛋白水平较低。在逐步多元逻辑回归分析中,发现有三个因素可独立预测重复头颅CT检查结果较差(表IV)。这包括年龄65岁及以上、格拉斯哥昏迷量表评分低于15分以及初次头颅CT检查时有多发创伤性颅内病变。总之,我们建议,对于轻度创伤性脑损伤且神经学检查正常的患者,无需进行重复头颅CT检查,因为这不会改变治疗方案或神经外科干预措施。对于有重复头颅CT检查结果恶化风险因素的部分患者,有必要进行密切监测。

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