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23例房室结折返性心动过速患者的结周冷冻消融术

Perinodal cryosurgery for atrioventricular node reentry tachycardia in 23 patients.

作者信息

Cox J L, Ferguson T B, Lindsay B D, Cain M E

机构信息

Department of Surgery, Washington University School of Medicine, Barnes Hospital, St. Louis, Mo. 63110.

出版信息

J Thorac Cardiovasc Surg. 1990 Mar;99(3):440-9; discussion 449-50.

PMID:2308362
Abstract

Atrioventricular node reentry tachycardia is the most common cause of paroxysmal supraventricular tachycardia. Available nonpharmacologic therapies include (1) catheter ablation or cryosurgical ablation of the His bundle and insertion of a permanent pacemaker and (2) surgical dissection around the atrioventricular node or discrete cryosurgery of the perinodal tissues, in an attempt to divide or ablate only one of the dual atrioventricular node conduction pathways responsible for the tachycardia while leaving the other intact. This report describes 23 consecutive patients who underwent the discrete cryosurgical procedure between August 13, 1982, and March 16, 1989. The first patient in this series, a 38-year-old woman, is the first patient in whom refractory atrioventricular node reentry tachycardia was cured surgically by a procedure designed to treat this arrhythmia. The ages of the 13 female and 10 male patients ranged from 12 to 56 years with an average age of 29 years. Fourteen of the 23 patients (61%) had the Wolff-Parkinson-White syndrome. Other associated arrhythmias included atrial flutter/fibrillation (n = 2), right atrial reentrant tachycardia (n = 1), junctional tachycardia (n = 1), and a Mahaim fiber (n = 1). Associated anatomic abnormalities included Ebstein's anomaly in two patients and a large right atrial aneurysm in one patient. The perinodal cryosurgical procedure was performed through a right atriotomy in the normothermic beating heart. Multiple 3 mm diameter cryolesions were placed around the borders of the triangle of Koch on the lower right atrial septum to alter the input pathways of the atrioventricular node. There were no operative deaths in this series of patients. Postoperatively, all 23 patients had normal atrioventricular conduction, and no heart block has occurred in any patients during the follow-up period. All patients have remained free of atrioventricular node reentry tachycardia (and of the Wolff-Parkinson-White syndrome) and none has required postoperative antiarrhythmic drugs for either of these arrhythmias. We consider this simple, safe, easily performed, and uniformly successful operation to be the procedure of choice for the treatment of medically refractory atrioventricular node reentry tachycardia.

摘要

房室结折返性心动过速是阵发性室上性心动过速最常见的病因。现有的非药物治疗方法包括:(1)对希氏束进行导管消融或冷冻手术消融,并植入永久性起搏器;(2)在房室结周围进行手术分离或对结周组织进行离散冷冻手术,试图仅分离或消融导致心动过速的双房室结传导通路中的一条,而使另一条保持完整。本报告描述了1982年8月13日至1989年3月16日期间连续接受离散冷冻手术的23例患者。该系列中的首例患者是一名38岁女性,是首例通过旨在治疗这种心律失常的手术治愈难治性房室结折返性心动过速的患者。13名女性和10名男性患者的年龄在12至56岁之间,平均年龄为29岁。23例患者中有14例(61%)患有预激综合征。其他相关心律失常包括心房扑动/颤动(n = 2)、右房折返性心动过速(n = 1)、交界性心动过速(n = 1)和一条Mahaim纤维(n = 1)。相关的解剖异常包括2例患者有埃布斯坦畸形和1例患者有巨大右房动脉瘤。结周冷冻手术是在常温跳动的心脏上通过右心房切开术进行的。在右房下部间隔的科赫三角边界周围放置多个直径3毫米的冷冻损伤灶,以改变房室结的输入通路。该系列患者中无手术死亡病例。术后,所有23例患者的房室传导均正常,随访期间无任何患者发生心脏传导阻滞。所有患者均未再发生房室结折返性心动过速(和预激综合征),且无一例患者因这些心律失常需要术后使用抗心律失常药物。我们认为这种简单、安全、易于实施且成功率一致的手术是治疗药物难治性房室结折返性心动过速的首选方法。

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