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视网膜的神经元组织。

The neuronal organization of the retina.

机构信息

Department of Opthamology, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.

出版信息

Neuron. 2012 Oct 18;76(2):266-80. doi: 10.1016/j.neuron.2012.10.002. Epub 2012 Oct 17.

Abstract

The mammalian retina consists of neurons of >60 distinct types, each playing a specific role in processing visual images. They are arranged in three main stages. The first decomposes the outputs of the rod and cone photoreceptors into ∼12 parallel information streams. The second connects these streams to specific types of retinal ganglion cells. The third combines bipolar and amacrine cell activity to create the diverse encodings of the visual world--roughly 20 of them--that the retina transmits to the brain. New transformations of the visual input continue to be found: at least half of the encodings sent to the brain (ganglion cell response selectivities) remain to be discovered. This diversity of the retina's outputs has yet to be incorporated into our understanding of higher visual function.

摘要

哺乳动物的视网膜由 >60 种不同类型的神经元组成,每种神经元在处理视觉图像方面都发挥着特定的作用。它们被排列在三个主要的阶段。第一阶段将视杆细胞和视锥细胞的输出分解成约 12 个平行的信息流。第二阶段将这些信息流连接到特定类型的视网膜神经节细胞。第三阶段将双极细胞和无长突细胞的活动结合起来,从而产生视网膜向大脑传输的视觉世界的多种编码方式——大约有 20 种。视觉输入的新转换仍在不断被发现:至少有一半发送到大脑的编码方式(神经节细胞反应的选择性)有待发现。这种视网膜输出的多样性尚未被纳入我们对高级视觉功能的理解中。

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