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对法医精神病住院患者进行维生素D缺乏筛查及治疗的可行性

Feasibility of screening for and treating vitamin D deficiency in forensic psychiatric inpatients.

作者信息

Murie Jill, Messow Claudia-Martina, Fitzpatrick Bridie

机构信息

NHS Scotland State Hospital and NHS Education for Scotland, 2 Central Quay, Glasgow G3 8BW, United Kingdom.

出版信息

J Forensic Leg Med. 2012 Nov;19(8):457-64. doi: 10.1016/j.jflm.2012.04.003. Epub 2012 May 4.

Abstract

Neuroleptic and anti-epileptic medication, inadequate vitamin D intake and limited solar exposure increase the risk of vitamin D deficiency in high security psychiatric environments. Of the 33 inpatients (40% selected; 21% of hospital population) completing this cross-sectional study, 36% had insufficient and 58% deficient vitamin D. Five patients with vitamin D deficiency had secondary hyperparathyroidism, two of whom had osteopenia on dual-emission X-ray absorptiometry. At 1-year follow up, of the 31 patients eligible, 15 had accepted and continued supplements. Systematic screening is therefore necessary due to mental health and consent issues. Implications of supplementation and grounds access are discussed.

摘要

在高度戒备的精神病环境中,使用抗精神病药物和抗癫痫药物、维生素D摄入不足以及日照有限会增加维生素D缺乏的风险。在完成这项横断面研究的33名住院患者中(占选定患者的40%;占医院总人数的21%),36%的患者维生素D水平不足,58%的患者维生素D缺乏。5名维生素D缺乏的患者患有继发性甲状旁腺功能亢进,其中2名患者在双能X线吸收测定法检查中显示骨质减少。在1年的随访中,31名符合条件的患者中有15名接受并继续服用补充剂。因此,由于心理健康和同意问题,进行系统筛查是必要的。本文讨论了补充剂的影响和获取途径。

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