Wessex Specialist Laser Centre, Salisbury District Hospital, Salisbury, SP2 8BJ, United Kingdom.
J Biomed Opt. 2012 Sep;17(9):90901-1. doi: 10.1117/1.JBO.17.9.090901.
A survey of the literature is presented that provides an analysis of the optical properties of human skin, with particular regard to their applications in medicine. Included is a description of the primary interactions of light with skin and how these are commonly estimated using radiative transfer theory (RTT). This is followed by analysis of measured RTT coefficients available in the literature. Orders of magnitude differences are found within published absorption and reduced-scattering coefficients. Causes for these discrepancies are discussed in detail, including contrasts between data acquired in vitro and in vivo. An analysis of the phase functions applied in skin optics, along with the remaining optical coefficients (anisotropy factors and refractive indices) is also included. The survey concludes that further work in the field is necessary to establish a definitive range of realistic coefficients for clinically normal skin.
本文对人体皮肤的光学特性进行了文献综述分析,尤其侧重于其在医学中的应用。文中描述了光与皮肤的主要相互作用,以及如何利用辐射传输理论(RTT)对这些作用进行常规估算。接着分析了文献中提供的已测量的 RTT 系数。在已发表的吸收和减散射系数中发现了数量级的差异。详细讨论了造成这些差异的原因,包括体外和体内数据之间的对比。本文还分析了皮肤光学中应用的相位函数以及其余光学系数(各向异性因子和折射率)。该综述得出结论,有必要在该领域开展进一步的工作,以确定临床正常皮肤的一套明确的实际系数范围。