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健康和新生血管化的人视网膜组织的光学散射、吸收和偏振

Optical scattering, absorption, and polarization of healthy and neovascularized human retinal tissues.

作者信息

Sardar Dhiraj K, Yow Ray M, Tsin Andrew T C, Sardar Ratna

机构信息

University of Texas at San Antonio, Department of Physics and Astronomy, San Antonio, Texas 78249-0697, USA.

出版信息

J Biomed Opt. 2005 Sep-Oct;10(5):051501. doi: 10.1117/1.2065867.

DOI:10.1117/1.2065867
PMID:16292945
Abstract

The optical scattering, absorption, and polarization properties of human retinal tissues are investigated for a number of laser wavelengths in the visible range. The indices of refraction of these tissues are determined by applying Brewster's law. The inverse adding doubling method based on the diffusion approximation and radiative transport theory is applied to the measured values of total diffuse transmission, total diffuse reflection, and index of refraction to determine the optical absorption, scattering, and scattering anisotropy coefficients of the intact retinal tissues from healthy and diseased (neovascularized) human eyes. The polarization studies show that the retinal tissues possess significant intrinsic polarization characteristics, that are more pronounced in diseased tissues than in healthy tissues.

摘要

针对可见光范围内的多个激光波长,研究了人体视网膜组织的光散射、吸收和偏振特性。通过应用布儒斯特定律来确定这些组织的折射率。基于扩散近似和辐射传输理论的逆相加加倍法应用于总漫透射、总漫反射和折射率的测量值,以确定来自健康和患病(新生血管化)人眼的完整视网膜组织的光吸收、散射和散射各向异性系数。偏振研究表明,视网膜组织具有显著的固有偏振特性,这些特性在患病组织中比在健康组织中更为明显。

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