Bishop Naomi B, Zhou Theresa X, Chen Jonathan M, Ward Mary J, Carroll Sheila J
Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY, USA.
Pediatr Cardiol. 2013 Mar;34(3):686-93. doi: 10.1007/s00246-012-0528-9. Epub 2012 Oct 21.
The impact of gestational age on perioperative morbidity was examined using a novel construct, the resource utilization index (RUI). The medical records of subjects from birth to 1 year of age entered into a pediatric cardiothoracic surgery database from a major academic medical center between 2007 and 2011 were reviewed. The hypothesis tested was that infants born at 37-38 weeks (early-term infants) experience greater resource utilization after open heart surgery than those born at 39 completed weeks and that this association can be observed until 1 year of age. The results support the premise that resource utilization increases linearly with declining gestational age among infants at 0-12 months who undergo cardiac surgery. Five of the six variables comprising the RUI showed statistically significant linear associations with gestational age in the predicted direction. Multivariate linear regression analysis showed that gestational age was a significant predictor of an increased RUI composite. Further investigation is needed to test the concept and to expand on these findings.
利用一种新的指标——资源利用指数(RUI),研究了胎龄对围手术期发病率的影响。回顾了2007年至2011年间一家大型学术医疗中心录入小儿心胸外科数据库的出生至1岁受试者的病历。所检验的假设是,孕37 - 38周出生的婴儿(早期足月儿)在心脏直视手术后的资源利用比孕39足周出生的婴儿更多,且这种关联在1岁前都可观察到。结果支持这样一个前提,即在接受心脏手术的0 - 12个月婴儿中,资源利用随胎龄下降呈线性增加。构成RUI的六个变量中有五个与胎龄呈统计学显著的线性关联,且方向符合预期。多变量线性回归分析表明,胎龄是RUI综合指数增加的一个显著预测因素。需要进一步研究来验证这一概念并拓展这些发现。