Herz D A, Looman J E, Tiberio A, Ketterling K, Kreitsch R K, Colwill J C, Grin O D
Division of Neurosurgery, Michigan State University, Grand Rapids.
Neurosurgery. 1990 Feb;26(2):300-6. doi: 10.1097/00006123-199002000-00018.
The treatment of spasticity in severely paralyzed patients undergoing rehabilitation constitutes a significant neurosurgical challenge that requires comprehensive management. In this study, 118 patients were treated with invasive modalities when medical therapy failed. The results of percutaneous radiofrequency foraminal rhizotomy were initially successful in 95% of the 77 patients who underwent this procedure; the rate of minor complications was 5%. This procedure was satisfactorily supplemented with percutaneous radiofrequency sciatic neurectomy in 32 of these 77 patients. Four myelotomies were performed with complete success and no major complications in patients in whom percutaneous techniques had proven inadequate. In 35 instances of focal spasticity and incomplete paralysis, intramuscular neurolysis by phenol injection was used. The success rate was 89%. In 9 patients with persistent recurrent spasticity of the lower limb, open tenotomies and peripheral neurectomies were done. Success was complete and without complications. Multiple modalities must be available for the comprehensive management of patients with paralytic spasticity.
对正在接受康复治疗的严重瘫痪患者的痉挛进行治疗是一项重大的神经外科挑战,需要综合管理。在本研究中,118例患者在药物治疗失败后接受了侵入性治疗方法。经皮射频椎间孔神经根切断术在77例接受该手术的患者中,初始成功率为95%;轻微并发症发生率为5%。在这77例患者中的32例中,该手术通过经皮射频坐骨神经切除术得到了令人满意的补充。在经皮技术已证明不足的患者中,进行了4例脊髓切开术,均完全成功且无重大并发症。在35例局灶性痉挛和不完全瘫痪的病例中,采用了苯酚注射进行肌肉内神经松解术。成功率为89%。在9例下肢持续性复发性痉挛患者中,进行了开放性肌腱切断术和周围神经切除术。手术完全成功且无并发症。对于瘫痪性痉挛患者的综合管理,必须具备多种治疗方法。