Moon Ji Yoon, Kim Gwang Ha, Cheong Jae Hoon, Lee Bong Eun, Ryu Dong Yup, Song Geun Am
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Korean J Gastroenterol. 2012 Oct;60(4):262-6. doi: 10.4166/kjg.2012.60.4.262.
Gastric hepatoid adenocarcinoma is a special type of gastric carcinoma, which produces AFP. We report a case of an metastatic gastric hepatoid adenocarcinoma mistaken for primary hepatocellular carcinoma (HCC). A 72 year-old woman was transferred to our hospital for treatment of the hepatic mass. She underwent subtotal gastrectomy for gastric cancer 2 years ago. A year ago, she was diagnosed with hepatic mass and treated with transhepatic chemoembolization under the suspicion of primary HCC in other hospital. The hepatic mass looked like primary HCC on CT, and serum AFP was elevated to 18,735 IU/mL. We did the transhepatic mass biopsy and compared it to the histology of the previous gastric cancer. The results of immunohistochemical staining between them was coincident, and so it was diagnosed as a hepatic metastasis of gastric hepatoid adenocarcinoma.
胃肝样腺癌是一种特殊类型的胃癌，可产生甲胎蛋白。我们报告一例转移性胃肝样腺癌被误诊为原发性肝细胞癌（HCC）的病例。一名72岁女性因肝脏肿块被转至我院治疗。她两年前因胃癌接受了胃大部切除术。一年前，她被诊断出肝脏肿块，在其他医院怀疑为原发性肝癌的情况下接受了经肝动脉化疗栓塞术。肝脏肿块在CT上看起来像原发性肝癌，血清甲胎蛋白升高至18735 IU/mL。我们对肝脏肿块进行了活检，并与之前胃癌的组织学进行了比较。两者之间的免疫组化染色结果一致，因此被诊断为胃肝样腺癌肝转移。
