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胰腺癌手术后慢性腹痛的植物疗法:单病例观察。

Phytotherapy of chronic abdominal pain following pancreatic carcinoma surgery: a single case observation.

机构信息

Department of True Naturopathy, Blankenstein Hospital, Hattingen, Germany.

出版信息

Int J Gen Med. 2012;5:845-8. doi: 10.2147/IJGM.S35635. Epub 2012 Oct 16.

DOI:10.2147/IJGM.S35635
PMID:23097614
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3476377/
Abstract

A patient with pancreatic carcinoma diagnosed in 2005 suffered from chronic abdominal pain 6 years later that did not respond to conventional pain treatment according to guidelines. Furthermore, several complementary medical approaches remained ineffective. In the long run, only an Iberis amara drug combination relieved pain sufficiently. The drug is registered in Germany for the indications irritable bowel syndrome and dyspepsia. The multi-target approach of this combination drug may account for the effectiveness under these fundamentally different pathophysiological conditions. No serious undesired effects have been described in the use of this drug for other indications and none were observed in this case.

摘要

一位 2005 年被诊断出患有胰腺癌的患者,6 年后出现慢性腹痛,根据指南,常规疼痛治疗无效。此外,几种补充医疗方法也没有效果。从长远来看,只有伊贝里斯苦艾组合药物才能充分缓解疼痛。该药物在德国被注册用于治疗肠易激综合征和消化不良。这种组合药物的多靶点方法可能是其在这些根本不同的病理生理条件下有效的原因。在用于其他适应症时,没有描述这种药物有严重的不良反应,在这种情况下也没有观察到。

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Phytotherapy of chronic abdominal pain following pancreatic carcinoma surgery: a single case observation.胰腺癌手术后慢性腹痛的植物疗法:单病例观察。
Int J Gen Med. 2012;5:845-8. doi: 10.2147/IJGM.S35635. Epub 2012 Oct 16.
2
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本文引用的文献

1
Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial.氟尿嘧啶+亚叶酸辅助化疗与观察对可切除的壶腹周围腺癌患者生存的影响:ESPAC-3 壶腹周围癌随机试验。
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Adenosine A2A receptor contributes to the anti-inflammatory effect of the fixed herbal combination STW 5 (Iberogast®) in rat small intestinal preparations.腺苷 A2A 受体有助于固定草药复方 STW 5(Iberogast®)在大鼠小肠制剂中的抗炎作用。
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The herbal extract, Iberogast, improves jejunal integrity in rats with 5-Fluorouracil (5-FU)-induced mucositis.草药提取物伊贝戈斯特可改善5-氟尿嘧啶(5-FU)诱导的大鼠空肠黏膜炎的肠完整性。
Cancer Biol Ther. 2009 May;8(10):923-9. doi: 10.4161/cbt.8.10.8146. Epub 2009 May 10.
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The multi-herbal drug STW 5 (Iberogast) has prosecretory action in the human intestine.多草药药物STW 5(伊贝戈斯特)在人体肠道中具有促分泌作用。
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Inhibition of inflammation-induced alterations in rat small intestine by the herbal preparations STW 5 and STW 6.草药制剂STW 5和STW 6对大鼠小肠炎症诱导性改变的抑制作用。
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[Assessment of the efficacy and safety of the phytopharmacon STW 5 versus metoclopramide in functional dyspepsia--a retrolective cohort study].[植物药STW 5与甲氧氯普胺治疗功能性消化不良的疗效及安全性评估——一项回顾性队列研究]
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[STW 5/Iberogast: multi-target-action for treatment of functional dyspepsia and irritable bowel syndrome].[STW 5/伊贝戈 Gast:治疗功能性消化不良和肠易激综合征的多靶点作用]
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STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study.STW 5,一种用于功能性消化不良患者的植物药:一项多中心、安慰剂对照双盲研究的结果。
Am J Gastroenterol. 2007 Jun;102(6):1268-75. doi: 10.1111/j.1572-0241.2006.01183.x.
9
Effects of Iberogast on proximal gastric volume, antropyloroduodenal motility and gastric emptying in healthy men.伊贝戈 Gast 对健康男性近端胃容积、胃幽门十二指肠运动及胃排空的影响。
Am J Gastroenterol. 2007 Jun;102(6):1276-83. doi: 10.1111/j.1572-0241.2007.01142.x. Epub 2007 Mar 22.
10
Spasmolytic and tonic effect of Iberogast (STW 5) in intestinal smooth muscle.伊比罗格斯(STW 5)对肠道平滑肌的解痉和强直作用。
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