Department of Radiology, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium,
Insights Imaging. 2012 Dec;3(6):603-10. doi: 10.1007/s13244-012-0197-5. Epub 2012 Oct 26.
To assess the diagnostic performance of 3D sampling perfection with application-optimised contrasts using variable flip-angle evolution (SPACE) turbo spin-echo (TSE) sequences compared to 2D TSE for comprehensive knee assessment at 3 T.
From January to July 2011, isotropic 3D SPACE was added to a 2D knee protocol at 3 T. Forty patients underwent subsequent arthroscopy. Three readers independently assessed MR images for meniscus, anterior cruciate ligament (ACL) and cartilage lesions. Readers 1 and 2 evaluated 3D and 2D data at separate sittings; reader 3 interpreted the complete exam including 3D and 2D sequences. Accuracies were calculated using arthroscopy as reference standard. McNemar's test (p < 0.05) was used to compare 3D and 2D techniques.
The highest diagnostic yield was obtained by reader 3 (accuracies ≥88 %). For the medial meniscus, readers performed better with the 2D technique than with 3D SPACE (accuracies 85-88 % vs. 78-80 %, respectively) (p > 0.05). For the lateral meniscus and ACL, 3D and 2D techniques had similar performance (accuracies ≥93 %). For cartilage lesions, 3D SPACE had significantly lower specificity (p = 0.0156) than the 2D protocol for one reader.
The conventional 2D TSE acquisition is more reliable than 3D SPACE for comprehensive assessment of the knee at 3.0 T.
• 3D SPACE is a valuable component of a knee MR protocol at 3 T. • 3D SPACE cannot be used as a single sequence in the MR evaluation of the knee at 3 T. • Knee MR protocols at 3 T should include both 2D and 3D TSE sequences.
在 3.0T 磁共振成像（MRI）中，评估使用可变翻转角演化（SPACE）涡轮自旋回波（TSE）序列的三维采样完美技术与二维 TSE 序列在全面膝关节评估中的诊断性能。
在 2011 年 1 月至 7 月期间，在 3.0T 磁共振扫描仪上添加了各向同性的三维 SPACE 序列到二维膝关节协议中。随后对 40 例患者进行了关节镜检查。三位读者分别独立评估 MRI 图像的半月板、前交叉韧带（ACL）和软骨病变。读者 1 和 2 在单独的检查中评估 3D 和 2D 数据；读者 3 则解释了包括 3D 和 2D 序列在内的完整检查。准确性使用关节镜检查作为参考标准进行计算。采用 McNemar 检验（p<0.05）比较 3D 和 2D 技术。
读者 3 的诊断准确率最高（≥88%）。对于内侧半月板，读者使用二维技术的准确率（85%-88%）高于三维 SPACE 技术（78%-80%）（p>0.05）。对于外侧半月板和 ACL，三维和二维技术的表现相似（准确率≥93%）。对于软骨病变，一位读者认为三维 SPACE 技术的特异性显著低于二维协议（p=0.0156）。
在 3.0T 磁共振成像中，常规的二维 TSE 采集比三维 SPACE 更可靠，适用于全面评估膝关节。
