Department of Biotechnology, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad, 500046 India.
Indian J Microbiol. 2009 Dec;49(4):320-3. doi: 10.1007/s12088-009-0057-2. Epub 2010 Jan 7.
Swine flu is a common term representing the respiratory viral infections caused by influenza A virus strain H1N1. This disease was noticed for the first time in Mexico during early 2009, spread worldwide very soon and took nearly 4000 lives. It is observed that this infection is due to an evolved virulent version of previously existing H1N1. The first report of this infection was noticed in a traveler from USA to India at the Hyderabad international airport. Later, because of its highly contagious and fast-spreading nature through air, many people reported to have the infection throughout the country. In Andhra Pradesh, there were 735 officially confirmed cases of which 44 died. These cases were not only from Hyderabad which is the state capital having frequent travelers from abroad but are also reported from different parts of the state. The incidence and mortality rate is less in Andhra Pradesh compared to some of the other Indian states. This raises a question whether the type of the strain is different or genetic features of the population is playing the role in reducing the severity of the disease. In this review we have discussed about the occurrence, spread and mortality of the current H1N1 pandemic. We have also discussed about the current status of research on H1N1 and efforts in the state of Andhra Pradesh.
猪流感是一个通用术语,代表由甲型流感病毒 H1N1 引起的呼吸道病毒感染。这种疾病于 2009 年初在墨西哥首次被发现,很快在全球范围内传播,并夺走了近 4000 人的生命。据观察,这种感染是由于先前存在的 H1N1 的进化毒力版本引起的。这种感染的第一份报告是在一名从美国到印度的旅客在海得拉巴国际机场发现的。后来,由于其通过空气高度传染性和快速传播的性质,全国各地有许多人报告感染了这种病毒。在安得拉邦,有 735 例官方确诊病例,其中 44 人死亡。这些病例不仅来自该邦首府海得拉巴,那里有来自国外的频繁旅行者,而且也有来自该邦不同地区的报告。与印度的一些其他邦相比,安得拉邦的发病率和死亡率较低。这引发了一个问题,即病毒株的类型是否不同,或者人口的遗传特征是否在减轻疾病严重程度方面发挥了作用。在这篇综述中,我们讨论了当前 H1N1 大流行的发生、传播和死亡率。我们还讨论了当前对 H1N1 的研究现状以及安得拉邦的努力。