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隐匿性耳源性脑脊液漏的诊断与外科治疗

The diagnosis and surgical treatment of occult otogenic CSF leakage.

作者信息

Yi H J, Zhao Li-Dong, Guo Wei, Wu N, Li J N, Ren L L, Liu P N, Yang S M

机构信息

Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China.

出版信息

Acta Otolaryngol. 2013 Feb;133(2):130-5. doi: 10.3109/00016489.2012.727468. Epub 2012 Oct 27.

Abstract

CONCLUSIONS

The diagnosis of occult otogenic cerebrospinal fluid (CSF) leakage is challenging and it can easily be misdiagnosed. Some characteristics of clinical presentation can supply important clues and confirmed diagnosis should be obtained according to these clues and suitable imaging studies before meningitis develops. Different surgical techniques should be adopted to treat the CSF leakage according to different leakage etiologies, and good results can be obtained.

OBJECTIVE

The aim of the study was to evaluate the diagnosis and surgical treatment of occult otogenic CSF leakage, including the characteristics of clinical presentation, imaging studies, and operation methods in order to decrease the rate of misdiagnosis and obtain a good curative effect.

METHODS

We performed a retrospective review of 11 cases of CSF leakage that were all misdiagnosed and accompanied by meningitis, operated in our department from 2007 to 2012 after a mean follow-up of 3 years. In this context, the characteristics of clinical presentation, imaging studies, and management of CSF leakage were studied.

RESULTS

The CSF leakage had arisen traumatically (n = 9) or congenitally (n = 2). The medical history and special clinical presentation such as repeated otorrhea or rhinorrhea, fever, headache, and unilateral deafness can supply important diagnostic clues. Imaging studies including high-resolution noncontrast CT (HRCT), CT cisternography, and magnetic resonance imaging (MRI) are very important diagnostic methods. The surgical repairs were performed via a transmastoid approach (n = 8), packing the vestibule (n = 1) or a translabyrithine approach (n = 2). Recurrent leakage did not occur.

摘要

结论

隐匿性耳源性脑脊液漏的诊断具有挑战性,很容易被误诊。临床表现的一些特征可提供重要线索,应根据这些线索及合适的影像学检查在脑膜炎发生前确诊。根据不同的漏出病因应采用不同的手术技术治疗脑脊液漏,可取得良好效果。

目的

本研究旨在评估隐匿性耳源性脑脊液漏的诊断及手术治疗,包括临床表现、影像学检查及手术方法的特点,以降低误诊率并获得良好疗效。

方法

我们对2007年至2012年在我科手术的11例均被误诊且伴有脑膜炎的脑脊液漏病例进行了回顾性研究,平均随访3年。在此过程中,研究了临床表现、影像学检查及脑脊液漏的处理情况。

结果

脑脊液漏为外伤性(n = 9)或先天性(n = 2)。病史及反复耳漏或鼻漏、发热、头痛和单侧耳聋等特殊临床表现可提供重要诊断线索。包括高分辨率非增强CT(HRCT)、CT脑池造影和磁共振成像(MRI)在内的影像学检查是非常重要的诊断方法。手术修复通过经乳突入路(n = 8)、填充前庭(n = 1)或经迷路入路(n = 2)进行。未发生复发性漏液。

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