Steadman Philippon Research Institute, Vail, Colorado, USA.
Arthroscopy. 2012 Dec;28(12):1819-25. doi: 10.1016/j.arthro.2012.06.016. Epub 2012 Oct 24.
The purpose of this study was to compare revision rates and outcomes after anterior cruciate ligament (ACL) reconstruction with bone-patellar tendon-bone (BPTB) autografts versus BPTB allografts in patients aged 18 years or younger with closed physes.
Institutional review board approval was obtained for this study. This study included 90 consecutive patients aged 18 years or younger with closed physes who underwent primary ACL reconstruction by a single surgeon between 1998 and 2009, with either BPTB autograft (n = 70) or BPTB allograft (n = 20). Patients who had concomitant ligament injuries were excluded. Outcome measures included the Lysholm score, Tegner activity scale, and patient satisfaction (0, very unsatisfied; 10, very satisfied). Failures were defined as cases requiring ACL revision surgery.
Of the 90 patients, 79 (88%) were contacted (20 of 20 with allografts and 59 of 70 with autografts). Of these 79 patients, 9 (11%) required revision ACL reconstruction. In the autograft group, 3% (2 of 59) required revision ACL reconstruction at a mean of 15.4 months (range, 13.0 to 17.7 months) after the index procedure. In the allograft group, 35% (7 of 20) required revision ACL reconstruction at a mean of 9.1 months (range, 5.3 to 12.0 months) after the index procedure. The allograft group was 15 (95% confidence interval [CI], 2 to 123) times more likely to require revision reconstruction than the autograft group (P = .001). The mean Lysholm score at follow-up was 85 (95% CI, 80.4 to 90.3) for the autograft group and 91 (95% CI, 88.1 to 97.3) for the allograft group (P = .46). The median Tegner activity scale was 7.0 (95% CI, 6.9 to 8.0) for autograft group and 6.5 (95% CI, 4.9 to 8.4) for the allograft group (P = .27). Median patient satisfaction score was 10 of 10 in both cohorts. No failures were seen in either group at 2 years postoperatively. Five of seven allograft failures occurred because of a premature return to sports.
No significant differences in function, activity, or satisfaction were found between allograft and autograft reconstructions in this patient population. The allograft group had a failure rate 15 times greater than that in the autograft group, with all failures occurring within the first year after reconstruction.
Level III, retrospective comparative study.
本研究旨在比较 18 岁及以下患者前交叉韧带(ACL)重建中使用骨-髌腱-骨(BPTB)自体移植物与同种异体移植物的翻修率和结果。
本研究获得了机构审查委员会的批准。该研究纳入了 1998 年至 2009 年间由同一位外科医生进行的 90 例连续的 18 岁及以下的 ACL 初次重建患者,分为 BPTB 自体移植物组(n = 70)和 BPTB 同种异体移植物组(n = 20)。排除合并有其他韧带损伤的患者。评估指标包括 Lysholm 评分、Tegner 活动量表和患者满意度(0,非常不满意;10,非常满意)。失败定义为需要进行 ACL 翻修手术的病例。
90 例患者中,有 79 例(88%)得到了随访(20 例同种异体移植物和 59 例自体移植物)。在这 79 例患者中,有 9 例(11%)需要进行 ACL 翻修重建。在自体移植物组中,3%(2/59)的患者在初次手术后 15.4 个月(范围,13.0 至 17.7 个月)需要进行 ACL 翻修重建。在同种异体移植物组中,35%(7/20)的患者在初次手术后 9.1 个月(范围,5.3 至 12.0 个月)需要进行 ACL 翻修重建。同种异体移植物组需要翻修重建的可能性是自体移植物组的 15 倍(95%置信区间,2 至 123)(P =.001)。自体移植物组的平均 Lysholm 评分为 85(95%置信区间,80.4 至 90.3),同种异体移植物组为 91(95%置信区间,88.1 至 97.3)(P =.46)。自体移植物组的中位数 Tegner 活动量表评分为 7.0(95%置信区间,6.9 至 8.0),同种异体移植物组为 6.5(95%置信区间,4.9 至 8.4)(P =.27)。两组患者的满意度中位数均为 10 分(满分 10 分)。两组患者在术后 2 年均无失败病例。同种异体移植物组的 5 例失败均因过早恢复运动所致。
在该患者人群中,自体移植物与同种异体移植物重建在功能、活动和满意度方面均无显著差异。同种异体移植物组的失败率是自体移植物组的 15 倍,所有失败均发生在重建后 1 年内。
III 级,回顾性比较研究。