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25 岁及以下人群中使用同种异体骨-髌腱-骨移植物或自体移植物进行前交叉韧带重建后的翻修率。

Revision rates after anterior cruciate ligament reconstruction using bone-patellar tendon-bone allograft or autograft in a population 25 years old and younger.

机构信息

Plano Orthopedic Sports Medicine and Spine Center, Plano, Texas, U.S.A.

出版信息

Arthroscopy. 2014 Apr;30(4):483-91. doi: 10.1016/j.arthro.2013.12.022.

Abstract

PURPOSE

To compare clinical outcomes and revision rates for anterior cruciate ligament (ACL) reconstructions using bone-patellar tendon-bone (BPTB) allografts versus BPTB autografts in a population of patients aged 25 years and younger.

METHODS

A consecutive series of patients 25 years or younger undergoing ACL reconstruction with either a patient-selected BPTB allograft or BPTB autograft fixed with biocomposite interference screws was retrospectively reviewed. Multiligamentous and posterior cruciate ligament tears were excluded. All allografts were from a single source and not chemically processed or irradiated. Two graft-specific rehabilitation programs were used. The primary outcome measure was graft failure. Failure was defined as a subsequent ACL revision surgery, 2+ Lachman test, positive pivot-shift, or side-to-side KT difference of greater than 5 mm. Secondary outcome measures included Cincinnati, Lysholm, and International Knee Documentation Committee (IKDC) activity scores.

RESULTS

In 81 patients at least 24 months after surgery (28 allografts; 53 autografts), 7 failures were identified: 2 of 28 (7.1%) allografts and 5 of 53 (9.4%) autografts. Mean Cincinnati scores improved from 54.6 and 39.5 (allografts and autografts, respectively) to 86.2 and 85.1. Mean Lysholm scores improved from 60.3 and 44.8 (allografts and autografts, respectively) to 89.9 and 87.0. Average KT differences were 0.59 mm (allograft) and 0.34 mm (autograft group) (P = .58). IKDC activity scores were 2.9 (allografts) and 3.1 (autografts) postoperatively (P = .32).

CONCLUSIONS

Using a patient-choice ACL graft selection program after appropriate counseling and using graft-specific rehabilitation programs, not chemically processed or irradiated BPTB allograft reconstructions have no greater failure rate than autografts in patients aged 25 years and younger at a minimum 2-year follow-up. No significant differences in Cincinnati, Lysholm, and IKDC activity scores were found between these 2 groups.

LEVEL OF EVIDENCE

Level III, retrospective comparative study.

摘要

目的

比较在 25 岁及以下患者中,使用同种异体骨-髌腱-骨(BPTB)移植物与自体 BPTB 移植物进行前交叉韧带(ACL)重建的临床结果和翻修率。

方法

回顾性分析了连续接受 ACL 重建的患者队列,这些患者使用患者选择的同种异体 BPTB 移植物或 BPTB 自体移植物,使用生物复合材料干扰螺钉固定。排除多韧带和后交叉韧带撕裂。所有同种异体移植物均来自单一来源,未经过化学处理或辐射。使用了两种特定于移植物的康复方案。主要结局测量指标是移植物失败。失败定义为随后的 ACL 翻修手术、2+Lachman 试验、阳性髌股关节移位试验或侧方间隙 KT 差值大于 5mm。次要结局测量指标包括辛辛那提、Lysholm 和国际膝关节文献委员会(IKDC)活动评分。

结果

在至少 24 个月手术后的 81 名患者中(28 例同种异体移植物;53 例自体移植物),发现 7 例失败:28 例同种异体移植物中有 2 例(7.1%),53 例自体移植物中有 5 例(9.4%)。辛辛那提评分从 54.6 和 39.5(同种异体移植物和自体移植物)分别提高到 86.2 和 85.1。Lysholm 评分从 60.3 和 44.8(同种异体移植物和自体移植物)分别提高到 89.9 和 87.0。平均 KT 差值分别为 0.59mm(同种异体移植物)和 0.34mm(自体移植物组)(P=0.58)。IKDC 活动评分分别为术后 2.9(同种异体移植物)和 3.1(自体移植物)(P=0.32)。

结论

在适当的咨询后,使用 ACL 移植物选择计划,使用未经化学处理或辐射的同种异体 BPTB 移植物重建,在 25 岁及以下患者中,2 年以上的随访中,其失败率与自体移植物没有显著差异。在这两组之间,辛辛那提、Lysholm 和 IKDC 活动评分没有显著差异。

证据水平

III 级,回顾性比较研究。

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