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特发性双侧纹状体-苍白球-齿状核钙化(法尔病):一例病例报告及文献综述

Idiopathic bilateral strio-pallido-dentate calcinosis (Fahr's disease): a case report and review of the literature.

作者信息

Abubakar Sani A, Saidu Suleiman

机构信息

Department of Medicine, Ahmadu Bello University Teaching Hospital Zaria, Nigeria.

出版信息

Ann Afr Med. 2012 Oct-Dec;11(4):234-7. doi: 10.4103/1596-3519.102855.

Abstract

Bilateral calcification involving the basal ganglia (Fahr's disease) is a rare disease. A high index of suspicion is required to make clinical diagnosis; more so that the calcinosis may remain asymptomatic in a vast majority of cases. Movement disorder is by far the most common manifestation in symptomatic individuals. Fahr's disease is by no means absent in our environment, and increasing availability of a computed tomography-scan machine in Nigeria may enhance the case identification of Fahr's disease. This review presents a case of bilateral strio-pallido-dentate calcification; it also affirms the fact that Fahr's disease could present with hyperkinetic movement disorder (chorea) in our setting.

摘要

双侧基底节钙化(法尔病)是一种罕见疾病。临床诊断需要高度怀疑指数;尤其是在绝大多数病例中,钙质沉着可能无症状。运动障碍是有症状个体中迄今为止最常见的表现。在我们所处的环境中,法尔病并非不存在,而且尼日利亚计算机断层扫描仪的可用性增加可能会提高法尔病的病例识别率。本综述介绍了一例双侧纹状体-苍白球-齿状核钙化病例;它也证实了在我们的环境中,法尔病可能表现为运动过多性运动障碍(舞蹈症)这一事实。

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