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Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia.

作者信息

Sandoval Juan, Heyn Holger, Méndez-González Jesús, Gomez Antonio, Moran Sebastian, Baiget Montserrat, Melo Montserrat, Badell Isabel, Nomdedéu Josep F, Esteller Manel

机构信息

Cancer Epigenetics and Biology Programme, Bellvitge Biomedical Research Institute, L Hospitalet de Llobregat, Barcelona, Catalonia, Spain.

出版信息

Br J Haematol. 2013 Feb;160(3):406-9. doi: 10.1111/bjh.12113. Epub 2012 Oct 30.

DOI:10.1111/bjh.12113
PMID:23110451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3568176/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54a0/3568176/12e1307297dd/bjh0160-0406-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54a0/3568176/12e1307297dd/bjh0160-0406-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54a0/3568176/12e1307297dd/bjh0160-0406-f1.jpg

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Blood. 2012 May 3;119(18):4152-61. doi: 10.1182/blood-2011-09-382390. Epub 2012 Mar 12.
2
Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks.核型正常的急性髓系白血病中具有预后意义的 DNA 甲基化模式由干细胞染色质标记预先确定。
Blood. 2011 Nov 17;118(20):5573-82. doi: 10.1182/blood-2011-01-332353. Epub 2011 Sep 29.
3
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome.
增殖史塑造了 B 细胞肿瘤的 DNA 甲基组,并预测了临床结果。
Nat Cancer. 2020 Nov;1(11):1066-1081. doi: 10.1038/s43018-020-00131-2. Epub 2020 Nov 2.
4
Prognostic and Predictive Value of Three DNA Methylation Signatures in Lung Adenocarcinoma.三种DNA甲基化特征在肺腺癌中的预后及预测价值
Front Genet. 2019 Apr 24;10:349. doi: 10.3389/fgene.2019.00349. eCollection 2019.
5
Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post-natal environmental exposures and risk of childhood acute lymphoblastic leukaemia.探讨 DNA 甲基化在宫内和产后环境暴露与儿童急性淋巴细胞白血病风险之间关系中的潜在机制作用。
Int J Cancer. 2019 Dec 1;145(11):2933-2943. doi: 10.1002/ijc.32203. Epub 2019 Mar 19.
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