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Phosphodiesterase-III Inhibitors Amrinone and Milrinone on Epilepsy and Cardiovascular Activities.

作者信息

Asif Mohammad

机构信息

Department of Pharmacy, GRD (PG) IMT, Dehradun, Uttarakhan, India E-mail:

出版信息

N Am J Med Sci. 2012 Oct;4(10):499-502. doi: 10.4103/1947-2714.102001.

DOI:10.4103/1947-2714.102001
PMID:23112975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3482785/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a52c/3482785/9c4f24a99c03/NAJMS-4-499-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a52c/3482785/9c4f24a99c03/NAJMS-4-499-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a52c/3482785/9c4f24a99c03/NAJMS-4-499-g001.jpg

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Bioorg Med Chem Lett. 2009 Oct 1;19(19):5791-5. doi: 10.1016/j.bmcl.2009.07.136. Epub 2009 Aug 6.
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Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone.6-(4-羧甲基氧苯基)-4,5-二氢-3(2H)-哒嗪酮的一些酰胺衍生物的合成及血管舒张活性。
Eur J Med Chem. 2009 Nov;44(11):4441-7. doi: 10.1016/j.ejmech.2009.06.006. Epub 2009 Jun 13.
3
Design, synthesis and structure-activity relationship studies of 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives as cardiotonic agents.
作为强心剂的6-苯基-4,5-二氢-3(2H)-哒嗪酮衍生物的设计、合成及构效关系研究
Arzneimittelforschung. 2008;58(11):569-73. doi: 10.1055/s-0031-1296558.
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Synthesis and evaluation of 2-substituted-6-phenyl-4,5-dihydropyridazin-3(2H)-ones as potent inodilators.2-取代-6-苯基-4,5-二氢哒嗪-3(2H)-酮作为强效强心扩血管药的合成与评价
Acta Pharm. 2008 Dec;58(4):393-405. doi: 10.2478/v1007-008-0021-4.
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The proconvulsant effect of sildenafil in mice: role of nitric oxide-cGMP pathway.西地那非对小鼠的促惊厥作用:一氧化氮 - 环鸟苷酸途径的作用
Br J Pharmacol. 2006 Apr;147(8):935-43. doi: 10.1038/sj.bjp.0706680.
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Pharmacological studies on mechanisms of aminophylline-induced seizures in rats.氨茶碱诱发大鼠癫痫发作机制的药理学研究。
Indian J Exp Biol. 2005 Oct;43(10):849-53.
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Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development.磷酸二酯酶:蛋白质结构概述、潜在治疗应用及药物研发最新进展
Cell Mol Life Sci. 2005 Jun;62(11):1198-220. doi: 10.1007/s00018-005-4533-5.
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