Layer F, Cuny C, Strommenger B, Werner G, Witte W
Nationales Referenzzentrum für Staphylokokken und Enterokokken, Robert Koch-Institut, Burgstrasse 37, Wernigerode, Germany.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Nov;55(11-12):1377-86. doi: 10.1007/s00103-012-1560-x.
Nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a problem in hospital settings worldwide. The National Reference Centre for Staphylococci performs molecular typing on a representative sample set of MRSA isolates from German hospitals for assessing long-term trends thus following the dynamics of emergence and spread of MRSA clones. The article focuses on recent data concerning antibiotic resistance and epidemic MRSA in nosocomial settings and also reflects the impact of community-acquired MRSA and MRSA from zoonotic reservoirs. Identifying common and newly emerging clones is an on-going challenge in the changing epidemiology of MRSA and prevention of further spread needs molecular surveillance.
耐甲氧西林金黄色葡萄球菌(MRSA)引起的医院感染是全球医院环境中的一个问题。葡萄球菌国家参考中心对来自德国医院的一组具有代表性的MRSA分离株样本进行分子分型,以评估长期趋势,从而追踪MRSA克隆的出现和传播动态。本文重点关注医院环境中有关抗生素耐药性和流行MRSA的最新数据,同时也反映了社区获得性MRSA和来自动物源性病原体库的MRSA的影响。在MRSA不断变化的流行病学中,识别常见和新出现的克隆是一项持续的挑战,预防进一步传播需要分子监测。