Fusco Roberta, Petrillo Antonella, Catalano Orlando, Sansone Mario, Granata Vincenza, Filice Salvatore, D'Aiuto Massimiliano, Pankhurst Quentin, Douek Michael
Department of Diagnostic Unit, National Cancer Institute, Pascale Foundation, via M. Semmola, 80131, Naples, Italy.
Breast Cancer. 2014 Sep;21(5):522-31. doi: 10.1007/s12282-012-0427-1. Epub 2012 Nov 2.
Accurate location of small breast lesions is mandatory for proper surgical management. The purpose of this article is systematically review procedures used to locate non-palpable breast lesions, including a description of the current status, advantages, and disadvantages for each technique. A total of 47 articles were finally included: 7 articles for the wire location technique, 5 articles for the radioguided location technique, 13 articles that compare wire location with radioguided location, 3 articles for the carbon location technique, 2 articles that compare wire location with carbon location, and 17 articles for the clip location technique. The success of location and the clear margin are reported for each location technique and for the separate articles included; clip migration shift, also, is reported for the clip location technique. Odds ratio with related 95 % confidence intervals were also calculated for successful location. Comparative analysis or meta-analysis for all the different breast lesion location techniques is missing. Prospective investigations and randomized investigations for homogeneous populations are still needed to determine which is the most cost-effective modality among those used to date.
准确确定小乳腺病变的位置对于恰当的手术治疗至关重要。本文旨在系统回顾用于定位不可触及乳腺病变的方法，包括对每种技术的现状、优点和缺点的描述。最终共纳入47篇文章：7篇关于金属丝定位技术，5篇关于放射性引导定位技术，13篇比较金属丝定位与放射性引导定位，3篇关于碳定位技术，2篇比较金属丝定位与碳定位，17篇关于夹子定位技术。报告了每种定位技术以及所纳入各篇文章的定位成功率和切缘清晰情况；对于夹子定位技术，还报告了夹子移位情况。还计算了成功定位的比值比及其相关的95%置信区间。目前缺少对所有不同乳腺病变定位技术的比较分析或荟萃分析。仍需要针对同质人群进行前瞻性研究和随机研究，以确定目前所使用的方法中哪种是最具成本效益的方式。
