胃肠功能的发育：坏死性小肠结肠炎的危险因素。
Development of gastrointestinal function: risk factors for necrotizing enterocolitis.
作者信息
Clark David A, Mitchell Amy L
机构信息
Albany Medical College, Albany, New York.
出版信息
J Pediatr Pharmacol Ther. 2004 Apr;9(2):96-103. doi: 10.5863/1551-6776-9.2.96.
The intestinal tract of the fetus matures rapidly in the third trimester of the pregnancy. The premature infant has decreased intestinal motility, limited digestion, absorption and excretion, and poor intestinal barrier defense. These limitations place the infant at high risk for acute intestinal injury, necrotizing enterocolitis. This article reviews the development of the gastrointestinal tract in the fetus, the barriers to feeding the high risk, premature infant, and the most serious intestinal disease, necrotizing enterocolitis.
胎儿的肠道在妊娠晚期迅速成熟。早产儿肠道蠕动减弱，消化、吸收和排泄功能受限，肠道屏障防御功能差。这些限制使婴儿面临急性肠道损伤、坏死性小肠结肠炎的高风险。本文综述了胎儿胃肠道的发育、高危早产儿喂养的障碍以及最严重的肠道疾病——坏死性小肠结肠炎。
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