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老年人癌症患者与非癌症患者的流感免疫接种。

Influenza immunization in older adults with and without cancer.

机构信息

Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

J Am Geriatr Soc. 2012 Nov;60(11):2099-103. doi: 10.1111/j.1532-5415.2012.04196.x. Epub 2012 Nov 5.

Abstract

OBJECTIVES

To compare the likelihood of receiving an influenza immunization in older adults before and immediately after a cancer diagnosis occurring in 2001 and for the same time periods with older adults not diagnosed with cancer.

DESIGN

Retrospective analysis comparing influenza immunization rates of Medicare beneficiaries with and without a diagnosis of cancer.

SETTING

Surveillance, Epidemiology, and End Results-Medicare Data.

PARTICIPANTS

Propensity score matching matched a group of 35,229 persons without cancer with 35,257 individuals diagnosed with cancer in 2001.

MEASUREMENTS

Receipt of influenza vaccination based upon Medicare Claims Data.

RESULTS

A difference-of-difference analysis revealed that influenza immunization rates increased over time for persons diagnosed with cancer (46.8% before to 50.8% after cancer diagnosis), but the increase was greater in beneficiaries without a cancer diagnosis (42.6% to 79.7%) (P < .001; 95% confidence interval = 0.320-0.324). Logistic regression analysis revealed that individuals without a cancer diagnosis were 7.25 times as likely to receive an influenza immunization.

CONCLUSION

Older adults who have been recently diagnosed with cancer receive influenza immunizations at much lower rates than older adults who have not been diagnosed with cancer despite interaction with healthcare providers. Opportunities exist to improve influenza immunization in this population, who are susceptible to influenza because of compromised immune systems.

摘要

目的

比较 2001 年癌症确诊前后和同一时期老年人群中接受流感免疫接种的可能性,比较对象为确诊癌症和未确诊癌症的老年人群。

设计

回顾性分析比较有和无癌症诊断的 Medicare 受益人的流感免疫接种率。

地点

监测、流行病学和最终结果-Medicare 数据。

参与者

采用倾向评分匹配,将 2001 年无癌症的 35229 人和诊断为癌症的 35257 人匹配在一起。

测量

基于 Medicare 理赔数据评估流感疫苗接种情况。

结果

差异分析显示,癌症确诊患者的流感免疫接种率随时间推移而增加(癌症确诊前为 46.8%,确诊后为 50.8%),但无癌症诊断的受益人的增幅更大(42.6%至 79.7%)(P<0.001;95%置信区间=0.320-0.324)。逻辑回归分析显示,未患癌症的个体接受流感免疫接种的可能性是已患癌症个体的 7.25 倍。

结论

尽管与医疗保健提供者进行了互动,但最近被诊断患有癌症的老年人群接受流感免疫接种的比率要低得多,而未被诊断患有癌症的老年人群接受流感免疫接种的比率要高得多。由于免疫系统受损,这一人群易患流感,因此有机会改善这一人群的流感免疫接种。

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