Shibata H, Sogou M, Ozaki A, Obara J
Radioisotopes. 1979 Oct 15;28(10):618-23. doi: 10.3769/radioisotopes.28.10_618.
In order to clarify the suitability of 198Au-colloid and Na251CrO4 as a marker of transit of the gastrointestinal content of the chicken, the distribution, absorption and excretion of 198Au-colloid and Na251CrO4 in the chicken were examined. Orally administered 198Au-colloid was not absorbed by the gastrointestinal tract and excreted into feces. Intravenously injected 198Au-colloid was not excreted into the gastrointestinal tract through the gastrointestinal wall. On the other hand, orally administered Na251CrO4 was relatively well absorbed by the gastrointestinal tract and distributed over a whole body. Intravenously injected Na251CrO4 was excreted into the gastrointestinal tract through the gastrointestinal wall and bile ducts. It seemed that 198Au-colloid was not adhered to the gastrointestinal mucosa and consequently, the transport of 198Au-colloid in the gastrointestinal tract was not delayed. It is concluded that 198Au-colloid is highly suitable as a marker of gastrointestinal transit of the chicken but Na251CrO4 is unsuitable.
为了阐明198Au胶体和Na251CrO4作为鸡胃肠道内容物转运标志物的适用性,对198Au胶体和Na251CrO4在鸡体内的分布、吸收和排泄情况进行了研究。口服的198Au胶体未被胃肠道吸收,而是随粪便排出。静脉注射的198Au胶体不会通过胃肠道壁排泄到胃肠道中。另一方面,口服的Na251CrO4被胃肠道较好地吸收并分布于全身。静脉注射的Na251CrO4通过胃肠道壁和胆管排泄到胃肠道中。似乎198Au胶体未附着于胃肠道黏膜,因此,198Au胶体在胃肠道中的转运未被延迟。得出的结论是,198Au胶体非常适合作为鸡胃肠道转运的标志物,而Na251CrO4则不适合。