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以198Au胶体为标志物研究鸡的胃肠转运(作者译)

[Gastrointestinal transit in the chicken using 198Au-colloid as a marker (author's transl)].

作者信息

Shibata H, Sogou M

出版信息

Radioisotopes. 1982 Feb;31(2):82-7.

PMID:6283603
Abstract

Gastrointestinal transit in the chicken was investigated by using 198Au-colloid as a marker. Gastrointestinal transit was determined following administration of a 198Au-colloid solution (370 kBq (10 microCi), 0.5 ml) into the proventriculus by measuring the distribution of radioactivity in the gastrointestine. Most of 198Au-colloid administered into the proventriculus was transferred instantly to the gizzard and subsequently, some part of it quickly to the duodenum and the upper segment of the jejunoileum. A considerable quantity of 198Au-colloid in the duodenum, the upper and middle segment of the jejunoileum regurgitated to the gizzard. 198Au-colloid transferred to the caecum was retained for a long time (more than 48 hours) in these segments. A part of 198Au-colloid was found in the feces 90 to 120 minutes after administration into the proventriculus and the greater part of it was excreted into the feces 24 to 48 hours. Subcutaneous administration of acetylcholine (2 mg/kg) increased the gastrointestinal transit but atropine (2 mg/kg) decreased.

摘要

以198Au胶体为标志物研究了鸡的胃肠转运。通过测量胃肠内放射性分布,在将198Au胶体溶液(370 kBq(10微居里),0.5毫升)注入腺胃后测定胃肠转运。注入腺胃的198Au胶体大部分立即转移到肌胃,随后部分迅速转移到十二指肠和空肠回肠上段。十二指肠、空肠回肠上段和中段的大量198Au胶体会反流到肌胃。转移到盲肠的198Au胶体在这些部位会停留很长时间(超过48小时)。在注入腺胃90至120分钟后,粪便中发现一部分198Au胶体,大部分在24至48小时内排出到粪便中。皮下注射乙酰胆碱(2毫克/千克)可加快胃肠转运,但阿托品(2毫克/千克)则会减慢。

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