Siriluck Anunnatsiri, Thavornpitak Yupa
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
J Med Assoc Thai. 2012 Jul;95 Suppl 7:S143-8.
Human immunodeficiency virus (HIV) infection continues to be a major health problem worldwide. Whether several intervention programs are successful enough to ameliorate the significant hospitalization burden created by these patients is not known.
To analyze the burden of HIV infection on patient-hospitalization and death in the adult population using in-patient information from the three health insurance coverage schemes from the fiscal year 2010.
The authors analyzed the data on in-patients with ICD-10 coding B20-B24 HIV disease to obtain the admission and mortality rate, length of hospital stay and hospital charges.
The admission rate among adult HIV-infected patients was 91.8 times per 100,000 adult population. The most common age group affected by the disease was the 26-40 year-olds (59%). The most common condition causing hospitalization was opportunistic infection (83.6%), of which tuberculosis was the highest. The mortality rate was 10.3% and increasing with age. AIDS-related symptoms, malignancy and opportunistic infections were the major impacts on mortality.
HIV/AIDS still constitutes a major disease burden among the adult Thai population. Increased public awareness and prevention and access to early HIV diagnosis and treatment could be key factors for lowering the burden of disease and improving clinical outcomes.
人类免疫缺陷病毒(HIV)感染仍是全球主要的健康问题。目前尚不清楚多项干预计划是否足以成功减轻这些患者造成的巨大住院负担。
利用2010财年三个医疗保险覆盖计划的住院患者信息,分析HIV感染对成年人群住院和死亡的负担。
作者分析了国际疾病分类第十版(ICD-10)编码为B20-B24的HIV疾病住院患者的数据,以获取入院率和死亡率、住院时间和住院费用。
成年HIV感染患者的入院率为每10万成年人口91.8次。受该疾病影响最常见的年龄组是26-40岁(59%)。导致住院的最常见情况是机会性感染(83.6%),其中结核病最为常见。死亡率为10.3%,且随年龄增长而上升。与艾滋病相关的症状、恶性肿瘤和机会性感染是对死亡率的主要影响因素。
HIV/艾滋病在泰国成年人群中仍然构成主要的疾病负担。提高公众意识、预防以及获得早期HIV诊断和治疗可能是减轻疾病负担和改善临床结果的关键因素。