Lermusiaux P, Derriennic H, Castellani L
Service de Chirurgie Cardio-vasculaire, Hôpital Trousseau, Tours.
J Mal Vasc. 1990;15(1):26-9.
Changes due to hormone activity and caval compression by the uterus were noted in venous hemodynamics of the lower limbs during pregnancy. The purpose of the study was to search for a possible incidence of these modifications on venous inflow ant outflow during mercury strain gauge plethysmography (fig. 1). A total of 183 subjects were distributed into 4 groups: (table I) nonpregnant women of childbearing age (controls = C) and women of the first (G1), second (G2) and third (G3) trimesters of gestation. Women with a history of phlebitis or pronounced varicosis were excluded. The figures for venous filling (table II, III et IV) (delta V) were 3.2 (C), 3.1 (G1), 2.64 (G2) and 2.04 (G3). There was a significant (P less than 0.001) reduction in G3 (and left-sided G2) delta V compared to that of controls. Maximum venous outflow (MVO) was 125.3 (G1), 123.7 (G2) and 123.5 (G3), showing no significant difference with controls (125.1). It is concluded that no significant change in MVO occurred during pregnancy, whereas there was a decrease in delta approximately greater than V during the third trimester. These results suggest that the latter parameter should not be considered as a criterion for diagnosis of phlebitis in the pregnant woman.
孕期下肢静脉血流动力学变化与激素活性及子宫对下腔静脉的压迫有关。本研究旨在探寻这些改变在汞应变容积描记法（图1）中对静脉流入和流出的可能影响。总共183名受试者被分为4组：（表I）育龄非孕妇（对照组 = C）以及妊娠第一（G1）、第二（G2）和第三（G3）孕期的女性。有静脉炎病史或明显静脉曲张的女性被排除。静脉充盈数据（表II、III和IV）（ΔV）分别为3.2（C）、3.1（G1）、2.64（G2）和2.04（G3）。与对照组相比，G3（以及左侧G2）的ΔV显著降低（P < 0.001）。最大静脉流出量（MVO）分别为125.3（G1）、123.7（G2）和123.5（G3），与对照组（125.1）无显著差异。结论是孕期MVO无显著变化，而在妊娠晚期ΔV约有下降。这些结果表明，后一参数不应被视为孕妇静脉炎诊断的标准。
