Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
Spine (Phila Pa 1976). 2013 Jan 15;38(2):E84-93. doi: 10.1097/BRS.0b013e31827b8a2d.
A biomechanical study of facet joint pressure after total disc replacement using cadaveric human cervical spines during lateral bending and axial torsion.
The goal was to measure the contact pressure in the facet joint in cadaveric human cervical spines subjected to physiologic lateral bending and axial torsion before and after implantation of a ProDisc-C implant.
Changes in facet biomechanics can damage the articular cartilage in the joint, potentially leading to degeneration and painful arthritis. Few cadaveric and computational studies have evaluated the changes in facet joint loading during spinal loading with an artificial disc implanted. Computational models have predicted that the design and placement of the implant influence facet joint loading, but limited cadaveric studies document changes in facet forces and pressures during nonsagittal bending after implantation of a ProDisc. As such, little is known about the local facet joint mechanics for these complicated loading scenarios in the cervical spine.
Seven osteoligamentous C2-T1 cadaveric cervical spines were instrumented with a transducer to measure the C5-C6 facet pressure profiles during physiological lateral bending and axial torsion, before and after implantation of a ProDisc-C at that level. Rotations at that level and global cervical spine motions and loads were also quantified. RESULT.: Global and segmental rotations were not altered by the disc implantation. Facet contact pressure increased after implantation during ipsilateral lateral bending and contralateral torsion, but that increase was not significant compared with the intact condition.
Implantation of a ProDisc-C does not significantly modify the kinematics and facet pressure at the index level in cadaveric specimens during lateral bending and axial torsion. However, changes in facet contact pressures after disc arthroplasty may have long-term effects on spinal loading and cartilage degeneration and should be monitored in vivo.
使用尸体人颈椎在侧屈和轴向扭转时进行全椎间盘置换后面关节压力的生物力学研究。
目的是测量尸体人颈椎在植入 ProDisc-C 植入物前后在生理侧屈和轴向扭转时关节突关节的接触压力。
关节突生物力学的变化会损坏关节内的关节软骨,可能导致退化和疼痛性关节炎。很少有尸体和计算研究评估在植入人工椎间盘后脊柱负荷时关节突关节负荷的变化。计算模型预测,植入物的设计和位置会影响关节突关节的负荷,但有限的尸体研究记录了在植入 ProDisc 后非矢状面弯曲过程中关节突力和压力的变化。因此,对于颈椎这些复杂的负荷情况,对于局部关节突关节力学知之甚少。
7 具 C2-T1 骨韧带颈椎尸体标本在 C5-C6 关节突处用换能器进行了仪器测量,以测量生理侧屈和轴向扭转时的关节突压力分布,在该水平植入 ProDisc-C 前后。还量化了该水平和整个颈椎运动和载荷。结果:椎间盘植入物不会改变整体和节段旋转。在同侧侧屈和对侧扭转时,植入后关节突接触压力增加,但与完整状态相比,增加不显著。
在尸体标本的侧屈和轴向扭转时,ProDisc-C 的植入不会显著改变指数水平的运动学和关节突压力。然而,椎间盘关节成形术后关节突接触压力的变化可能对脊柱负荷和软骨退化有长期影响,应在体内进行监测。