Pierson R N, Friedman M I, Tansey W A, Castellana F S, Enlander D, Huang P J
Semin Nucl Med. 1979 Oct;9(4):224-40. doi: 10.1016/s0001-2998(79)80011-2.
Some of the available cardiovascular nuclear medicine methods are incompletely validated, and others are incompletely developed. They are, however, of very great potential in diagnostic cardiology, and in patient management. A new era of clinical research and acute care monitoring has been opened by serial, noninvasive, hemodynamic measurements of right ventricular as well as left ventricular function. Stress testing has become more specific, and should, with future developments, become more specific, and should, with future developments, become more sensitive, using radionuclide procedures. Serious quality control and validation questions concerning thallium stress testing must be addressed. Intracoronary injection of radiogases has great potential, although minimal present application. Emission computerized tomography will be an important research tool. Compartmental analysis modeling of first pass tracer injections has much to offer, but is not yet validated. Present growth rate of these procedures is very rapid. Fully developed, cardiovascular nuclear medicine may become the largest component of clinical nuclear medicine practice.
现有的一些心血管核医学方法尚未得到充分验证,其他一些方法也尚未完全成熟。然而,它们在诊断心脏病学和患者管理方面具有巨大的潜力。通过对右心室和左心室功能进行连续、无创的血流动力学测量,开启了临床研究和急性护理监测的新时代。使用放射性核素程序,负荷试验已经变得更加特异,并且随着未来的发展,应该会变得更加特异和更加敏感。必须解决有关铊负荷试验的严重质量控制和验证问题。冠状动脉内注射放射性气体具有很大的潜力,尽管目前应用极少。发射计算机断层扫描将成为一项重要的研究工具。首次通过示踪剂注射的房室分析模型有很大的应用价值,但尚未得到验证。这些程序目前的增长速度非常快。全面发展后,心血管核医学可能会成为临床核医学实践的最大组成部分。