Taub Amy F, Tucker Robert D, Palange Andrea
Advanced Dermatology, Lincolnshire, IL, USA.
J Drugs Dermatol. 2012 Nov;11(11):1288-94.
Over the past 10 years, radiofrequency (RF) technology has been utilized for nonablative treatments for the treatment of rhytides and skin laxity. This manuscript reviews the scientific background of collagen synthesis in vivo and in response to RF energy as well as a clinical study of 17 patients receiving a series of facial treatments with a 4-MHz monopolar RF (Pellevé, Ellman International, Inc, Oceanside, NY). Clinical methods, results, and a review of the literature for RF aesthetic treatments of the face are presented.
Seventeen patients were treated in one site with 6 total treatments scheduled as follows: 1 session was performed every 15 days for 2 consecutive sessions, 1 session every month for 2 consecutive sessions, and 1 session every 2 months for 2 consecutive sessions. Both the treating physician and the patients via live viewing and comparison with baseline photographs performed assessment of results. Results are reported as averages across the 17 patients.
Two weeks after the first treatment, patients noted an overall average of 25% to 30% improvement. Just before the last or sixth treatment, there was an average of 50% improvement noted by the physician, with patients ranking an average self-improvement of 48%. The treating physician rated average improvement of 46% compared with baseline, whereas the patients ranked average improvement of 30% compared with baseline at 1 year after treatment was initiated (6 months after the final treatment). Patients find this treatment to be very well tolerated, with minimal to no discomfort and no downtime or significant side effects.
The Pellevé 4-MHz monopolar RF device is effective, safe, and very well tolerated for treating laxity, texture, and wrinkles of the skin without complication or discomfort. Evidence in the literature supports the scientific mechanism of action of acute collagen modification and continued neocollagenesis observed with the system. In this cohort, patients maintain approximately 50% improvement on average at 6 months and a 30% to 50% improvement 1 year after beginning the treatments, 6 months after completion.
在过去10年中，射频（RF）技术已被用于非消融治疗以改善皱纹和皮肤松弛。本文综述了体内胶原蛋白合成以及对射频能量反应的科学背景，以及一项对17例接受4兆赫单极射频（Pellevé，埃尔曼国际公司，纽约州奥申赛德）一系列面部治疗患者的临床研究。介绍了面部射频美容治疗的临床方法、结果及文献综述。
17例患者在一个部位接受6次治疗，具体安排如下：连续2次，每15天进行1次治疗；连续2次，每月进行1次治疗；连续2次，每2个月进行1次治疗。治疗医生和患者通过实时观察并与基线照片比较来评估结果。结果以17例患者的平均值报告。
首次治疗后两周，患者总体平均改善25%至30%。在最后一次即第六次治疗前，医生观察到平均改善50%，患者自评平均改善48%。治疗医生评估与基线相比平均改善46%，而在开始治疗1年后（最后一次治疗后6个月），患者评估与基线相比平均改善30%。患者发现这种治疗耐受性良好，几乎没有不适，无需停工，也没有明显副作用。
Pellevé 4兆赫单极射频设备在治疗皮肤松弛、质地和皱纹方面有效、安全且耐受性良好，无并发症或不适。文献中的证据支持该系统所观察到的急性胶原蛋白改性和持续新胶原蛋白生成的科学作用机制。在该队列中，患者在治疗开始后6个月平均维持约50%的改善，在完成治疗6个月后的1年中维持30%至50%的改善。
