Suppr超能文献

听神经鞘瘤的治疗管理。

Management of growing vestibular schwannomas.

机构信息

Department of Specialist Surgical and Anesthesiological Sciences, S. Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2013 Jul;270(7):2013-9. doi: 10.1007/s00405-012-2248-4. Epub 2012 Nov 8.

Abstract

Conservative management of small vestibular schwannomas is frequently proposed as most tumours do not grow. Anyway, tumour growth is reported in 30-40 % of the cases, so that surgery is consequently generally proposed. We primarily observed 161 patients affected by unilateral vestibular schwannomas. All patients were examined by means of gadolinium-enhanced magnetic resonance imaging scans. Tumour growth was recorded in 58 cases (35.8 %) and these subjects set up the group of study. Twenty-two (37.9 %) patients were surgically treated; tumour was always completely removed, all patients had normal facial function after surgery and only one patient suffered from a major complication (cerebellar haematoma). Fourteen patients (24.1 %) were submitted to radiotherapy, while one patient was lost at follow-up and another one died because of other medical reasons. Finally, 20 (34.5 %) subjects continued to be observed for different reasons. The mean follow-up period after identification of growth was 6.1 years. Nine tumours continued to grow, nine tumours stopped growing, one tumour grew and then regressed in size and one tumour decreased. Sixty percent of patients with useful hearing at diagnosis preserved it during the entire observation period. In conclusion, most of VS do not grow; in case of tumour growth, a surgical procedure may be suggested and the outcomes are not negatively influenced by the delay of the procedure. But in some cases, patients can still follow the "wait and scan" policy. In fact, only less than half of the growing tumours continued to grow. Moreover, most of the patients continued to retain a useful hearing.

摘要

对于小型前庭神经鞘瘤,通常建议采用保守治疗,因为大多数肿瘤不会生长。然而,有 30-40%的病例报告肿瘤会生长,因此通常会建议进行手术。我们最初观察了 161 例单侧前庭神经鞘瘤患者。所有患者均接受了钆增强磁共振成像扫描检查。在 58 例(35.8%)患者中记录到肿瘤生长,并将这些患者纳入研究组。其中 22 例(37.9%)患者接受了手术治疗;肿瘤均被完全切除,所有患者术后面部功能正常,仅 1 例患者出现严重并发症(小脑血肿)。14 例(24.1%)患者接受了放疗,1 例患者失访,另 1 例患者因其他医疗原因死亡。最后,20 例(34.5%)患者因各种原因继续接受观察。在发现肿瘤生长后,平均随访时间为 6.1 年。其中 9 个肿瘤继续生长,9 个肿瘤停止生长,1 个肿瘤生长后又缩小,1 个肿瘤减小。60%在诊断时具有有用听力的患者在整个观察期间保留了该听力。总之,大多数前庭神经鞘瘤不会生长;如果肿瘤生长,可建议进行手术,且手术延迟不会对结果产生负面影响。但在某些情况下,患者仍可遵循“等待和扫描”的策略。事实上,只有不到一半的生长肿瘤继续生长。此外,大多数患者仍保留有用听力。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验