Ylikorkala O, Kauppila A, Ollanketo M L
Acta Obstet Gynecol Scand. 1979;58(5):453-5. doi: 10.3109/00016347909154066.
Thirty-two women with hyperemesis gravidarum were treated with intramuscular ACTH (0.5 mg) or placebo for 4 days in a randomized double-blind trial. The two treatments were equally effective in relieving hyperemesis, although the function of the adrenal cortex was stimulated only during the ACTH therapy. The administration of ACTH thus appears useless for the treatment of severe vomiting in early pregnancy.
在一项随机双盲试验中，32名妊娠剧吐的女性接受了为期4天的肌肉注射促肾上腺皮质激素（0.5毫克）或安慰剂治疗。两种治疗在缓解妊娠剧吐方面同样有效，尽管仅在促肾上腺皮质激素治疗期间肾上腺皮质功能受到刺激。因此，促肾上腺皮质激素的给药对于治疗妊娠早期的严重呕吐似乎并无用处。
