Ludwig M E, LiVolsi V A, McMahon R T
Am J Surg Pathol. 1979 Oct;3(5):457-62. doi: 10.1097/00000478-197910000-00008.
This paper reports a case of carcinoma arising in a benign mixed tumor of lacrimal gland following multiple recurrences. The patient had eight recurrences of the benign lesion and after 32 years developed an adenocarcinoma associated with recurrent nodules of still recognizable benign mixed tumor. The literature on malignant mixed tumors of the lacrimal gland is reviewed noting the confusion in diagnostic terminology in early reports. Our patient illustrates the resemblance between malignant mixed tumor (carcinoma arising in pleomorphic adenoma) of lacrimal and salivary gland both clinically and pathologically.
本文报告1例泪腺良性混合瘤多次复发后发生癌变的病例。该患者良性病变复发8次，32年后出现腺癌，伴有仍可辨认的良性混合瘤复发结节。本文回顾了泪腺恶性混合瘤的相关文献，指出早期报告中诊断术语存在混淆。我们的患者在临床和病理上均显示出泪腺和涎腺恶性混合瘤（多形性腺瘤中发生的癌）之间的相似性。
