从特应性皮炎患者和健康个体的皮肤中分离的白念珠菌 rRNA 基因间区的序列多样性。

Sequence diversity of the intergenic spacer region of the rRNA gene of Cryptococcus albidus isolated from the skin of patients with atopic dermatitis and healthy individuals.

机构信息

Department of Microbiology, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan.

出版信息

Microbiol Immunol. 2013 Jan;57(1):74-6. doi: 10.1111/1348-0421.12003.

DOI:10.1111/1348-0421.12003

Abstract

The yeast species Cryptococcus albidus var. albidus was found to more often colonize the skin surface of patients with atopic dermatitis (77.0%, 47/61) than that of healthy subjects (37.5%, 15/40). The intergenic spacer 1 region of the rRNA gene of this species consists of four sequence types: I, II, III and IV. Types I and II were predominant among healthy subjects and atopic dermatitis patients, respectively.

摘要

白色念球菌变种白色亚种在特应性皮炎患者（77.0%，47/61）的皮肤表面比健康个体（37.5%，15/40）更常定植。该菌种的 rRNA 基因的间区 1 区域由四种序列类型组成：I、II、III 和 IV。类型 I 和 II 分别在健康个体和特应性皮炎患者中占优势。